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MetabolomicsUHPLC-Q-TOF MS-Based Serum Metabolomics Reveals the Therapeutic Effects of Berberine and Wumei Wan on APCmin/+ Mice

APCmin/+ mice (8-week-old) and wild-type C57BL/6 controls were divided into MOD (saline), BBR (100 mg/kg berberine), WMW (17 g/kg Wu Mei Wan), and CON (saline) groups. All mice received daily gavage for 10 weeks under a 60% high-fat diet. Serum samples were collected after euthanasia and subjecte...

2025-10-16 | MTBLS12598 | MetaboLights
TranscriptomicsTranscriptome profiling reveals a novel role for Trichostatin A in antagonizing histone chaperone Chz1 mediated telomere anti-silencing.
The histone chaperones play an important role in chromatin assembly and disassembly during replication and transcription. We assessed the global roles of histone chaperones in Saccharomyces cerevisiae. Microarray transcriptional analyses indicate that histone chaperones have their own specific targe...
ORGANISM(S): Saccharomyces cerevisiae 
2011-06-28 | E-GEOD-30228 | biostudies-arrayexpress
ProteomicsProteomics of P granules Z granules and Mutator foci in C.elegans
To examine the protein composition of germ granules subcompartments of C. elegans, while ensuring their physiological integrity, we utilized TurboID-based proximity biotin labeling techniques to idedtify the protein components of P granules, Z granules and Mutator foci in the germline of C.elegans.
ORGANISM(S): Caenorhabditis elegans 
2024-07-14 | PXD046498 | Pride
P granules z granules  mutator foci  proteomics c.elegans 
Proteomicsmice Renal tubular epithelial cells LC-MS/MS
Diabetic nephropathy is considered one of the most common microvascular complications of diabetes and the pathophysiology involves multiple factors. Progressive diabetic nephropathy is believed to be related to the structure and function of the tubular epithelial cells in the kidney. However, the ro...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-17 | PXD029651 | Pride
Mouse Renal tubular epithelial cells Lc-ms/ms 
TranscriptomicsPopulus tricho Raw sequence reads
We performed RNA-Seq of P. trichocarpa calluses that were firstly induced from roots. Then the total RNAs were isolated from the control and salt-stressed calluses (200 mM NaCl for 6, 12, 24, and 48 h) using a CTAB procedure. Note: All samples in SRA were assigned the same sample accession (SRS93853...
ORGANISM(S): Populus trichocarpa 
2015-06-01 | E-MTAB-4364 | biostudies-arrayexpress
UnknownA non-ionic fluorinated p-dopant enables the construction of efficient and stable perovskite solar cells.
Not available
S-EPMC12356144 | biostudies-literature
TranscriptomicsGenome-wide transcriptome analysis of gametophyte development in Physcomitrella patens
Gene expression was analyzed with digital gene expression tag profiling (DGEP) with samples taken from P. patens protonema at 3, 14 and 24 days, and also from or leafy shoot tissues l at 30 days after protoplastes isolated, and from 14-day-old caulonemal and chloronemal tissues. Totally, 4333 genes ...
ORGANISM(S): Physcomitrella patens 
2011-12-20 | E-GEOD-33279 | biostudies-arrayexpress
UnknownCangfu Daotan Wan alleviates polycystic ovary syndrome with phlegm-dampness syndrome via disruption of the PKP3/ERCC1/MAPK axis.
Not available
S-EPMC10327183 | biostudies-literature
UnknownCryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme.
Not available
S-EPMC6565675 | biostudies-literature
ProteomicsPRMT3 reverses HIV-1 latency by increasing chromatin accessibility to form a TEAD4-P-TEFb-containing transcriptional hub
A major challenge to the current efforts to cure HIV-1 infection is the persistence of latent viruses. Addressing this challenge hinges on unraveling the intricate interplay between the host and viral factors that are key for HIV-1 latency. Current antiretroviral agents effectively prevent actively ...
ORGANISM(S): Homo Sapiens 
2025-03-25 | PXD062187 |
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