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ProteomicsProteomics analysis on SETD2 deficient intestinal epithelial cells
SETD2 is a methyltransferase critical for the integrity of epithelial barrier. However, the role of SETD2 in safeguarding epithelial barrier integrity remains largely unexplored. Here, we performed proteomics analysis on intact intestinal barrier with SETD2 present and compromised intestinal barrier...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-04-06 | PXD055747 | Pride
Proteomics ip-ms 
ProteomicsThiol metabolic heterogeneity in immune cells causes distinct molecular mechanisms of toxicity upon chronic lead exposure
Lead pollution is global, billions of people are chronically exposed to lead. Biological thiols are nature sequesters of lead. Human immune system is highly vulnerable to lead, unfortunately the underlying mechanism remains unknown. Using mass cytometry and mass spectrometry, we systematically ident...
ORGANISM(S): Homo Sapiens Mus Musculus 
2024-10-30 | PXD057344 |
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