Serum samples were collected from patients with PsA to create a biomarker discovery cohort and a validation cohort. Patients with PsA were classified into axial or peripheral subtypes based on imaging criteria. Liquid chromatography-mass spectrometry was used in the discovery phase to screen for bio...
To investigate the important function of membrane protein TMEM225 in sperm, we constructed Tmem225 knockout mice. Sperm from knockout mice and control mice were isolated for proteomic analysis.
Background: Metabolic dysfunction–associated steatotic liver disease (MASLD) progresses from simple steatosis to metabolic dysfunction–associated steatohepatitis (MASH), yet its therapeutic development has been hampered by pathological complexity and heterogeneity. Methods: Bulk RNA-seq and diet-in...
