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MetabolomicsA novel strategy for mining and identification of acylcarnitines using data-independent-acquisition (DIA) based retention time prediction modeling and pseudo-characteristic fragmentation ions matching
It is a challenging work to screen, identify, and quantify acylcarnitines in complex biological samples. A method, based on the retention time (RT) prediction and data-independent acquisition strategies, was proposed for the large-scale identification of acylcarnitines using liquid chromatography co...
2021-10-06 | MTBLS1932 | MetaboLights
TranscriptomicsComparative analysis of D. shibae wild-type vs. delta-luxI1 supplemented with different acetylated homoserine-lactones
Comparison of a quorum sensing null mutant supplemented with C18-HSL, C18en-HSL, C18dien-HSL with D. shibae wild-type in order to identify traits induced by distinct autoinducers in this organism. Loop-design, two to three biological replicates of D. shibae wild-type, delta-luxI1 and delta-luxI1 sup...
ORGANISM(S): Dinoroseobacter shibae DFL 12 
2012-11-03 | E-GEOD-42010 | biostudies-arrayexpress
TranscriptomicsCell-density resolved comparative analysis of D. shibae wild-type vs. delta-luxI1
A quorum sensing null mutant was compared with D. shibae wild-type in order to identify quorum sensing controlled traits in this organism. Samples were taken at different optical densities in the exponential phase and in the stationary phase in order to clarify if quorum sensing regulation is depend...
ORGANISM(S): Dinoroseobacter shibae DFL 12 
2012-11-03 | E-GEOD-42011 | biostudies-arrayexpress
TranscriptomicsCell-density resolved comparative analysis of D. shibae wild-type vs. delta-luxI1 overexpressing luxI1 in trans
D. shibae delta-luxI1 overexpressing the luxI1 gene in trans was compared to the wild-type in order to identify quorum sensing controlled traits in this organism. Samples were taken at different optical densities in the exponential phase and in the stationary phase. Samples from Dinoroseobacter shib...
ORGANISM(S): Dinoroseobacter shibae DFL 12 
2012-11-03 | E-GEOD-42012 | biostudies-arrayexpress
MetabolomicsNQO1 protects obese mice through improvements in glucose and lipid metabolism.
Chronic nutrient excess leads to metabolic disorders and insulin resistance. Activation of stress-responsive pathways via Nrf2 activation contributes to energy metabolism regulation. Here, inducible activation of Nrf2 in mice and transgenesis of the Nrf2 target, NQO1, conferred protection from diet-...
2024-05-23 | MTBLS2085 | MetaboLights
ProteomicsPrediction and experimental validation of a new salinity-responsive cis-regulatory element (CRE) in tilapia
Quantitative DIA proteomics in combination with the transcription inhibitor actinomycin D was performed on the tilapia OmB cell line to identify proteins that are upregulated by transcriptional regulation during hyperosmotic stress. This analysis revealed proteins that are transcriptionally up-regul...
ORGANISM(S): Oreochromis Mossambicus 
2022-09-25 | PXD032181 | panorama
Unknown561. Safety of Remdesivir vs Standard Care in Patients with Moderate Covid-19
Not available
S-EPMC7777368 | biostudies-literature
UnknownActivating NOTCH1 Mutations Define a Distinct Subgroup of Patients With Adenoid Cystic Carcinoma Who Have Poor Prognosis, Propensity to Bone and Liver Metastasis, and Potential Responsiveness to Notch1 Inhibitors.
Not available
S-EPMC5456373 | biostudies-literature
UnknownUp-regulation of SNHG6 activates SERPINH1 expression by competitive binding to miR-139-5p to promote hepatocellular carcinoma progression.
Not available
S-EPMC6681790 | biostudies-literature
UnknownRNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer.
Not available
S-EPMC6307166 | biostudies-literature
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