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TranscriptomicsLiver tissue from the "Four Core Genotype" treated group C57BL/6J mice versus pool C57BL/6J mice of chow diet Liver
The purpose of this experiment was to determine the expression traits in Liver tissue from the Four Core Genotype treated group. Keywords: Sry transgene Four Core Genotype Mouse liver Tissue Liver tissue from the "Four Core Genotype" treated group consists of 20 female and male C57BL/6J mice fed a c...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-13264 | biostudies-arrayexpress
TranscriptomicsObesity study in transgenic and knockout animals
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-12000 | biostudies-arrayexpress
TranscriptomicsLiver tissue from hormone treated C57BL/6J mice versus pool C57BL/6J mice of chow diet Liver
The purpose of this experiment was to determine the expression traits in animals of inbred strain C57BL/6J, treated with gonadal hormones. (N=40, 20 males and 20 females). Liver tissue from the hormone treated group consists of 40 female and male C57BL/6J mice fed a chow diet containing 4% fat (Rals...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-13265 | biostudies-arrayexpress
TranscriptomicsAortic arch profiling of Apoe knockout mice
Aortic arch profiling of Apoe-/- mice fed a high fat diet (HFD, Harlan Teklad 88137, 21% fat, 0.15% cholesterol) starting at 8 weeks of age for 8, 16, and 24 weeks. B6 mice fed HFD for 16 weeks starting at 8 weeks of age were used as controls. Apoe-/- mice were fed a high fat diet (HFD, Harlan Tekl...
ORGANISM(S): Mus musculus 
2010-06-22 | E-GEOD-18443 | biostudies-arrayexpress
TranscriptomicsAortic arch profiling of Ldlr knockout mice with human CETP transgene
Aortic arch profiling of Ldlr-/- huCETP transgenic mice fed a low fat, cholesterol-containing western diet (LFWD, 9% fat, 0.15% cholesterol) starting at 8 weeks of age for 4, 8, 12, and 16 weeks. Ldlr-/- huCETP transgenic mice were fed a low fat, cholesterol-containing western diet (LFWD, 9% fat, ...
ORGANISM(S): Mus musculus 
2010-06-22 | E-GEOD-18442 | biostudies-arrayexpress
TranscriptomicsIdentification and validation of causal genes for atherosclerosis in mice
Identification of causal genes for atherosclerosis in a segregating mouse population and validation via single-gene knockout and plaque progression mouse models. This SuperSeries is composed of the following subset Series: GSE18442: Aortic arch profiling of Ldlr knockout mice with human CETP transg...
ORGANISM(S): Mus musculus 
2010-06-23 | E-GEOD-18479 | biostudies-arrayexpress
TranscriptomicsExpression profiling of Adipose tissue from C57BL/6J X C3H/HeJ)F2 and (C3H/HeJ X C57BL/6J )F2
The purpose of this experiment was to determine the expression traits in animals from F2 intercross of inbred strains C57BL/6J, C3H/HeJ. (N=309, 164 males and 145 females). Adipose from 295 F2 female and male mice were generated by intercrossing F1 mice. Mice were fed chow diet containing 4% fat (Ra...
ORGANISM(S): Mus musculus 
2009-08-09 | E-GEOD-11065 | biostudies-arrayexpress
TranscriptomicsExpression profiling of Liver tissue from C57BL/6J X C3H/HeJ)F2 and (C3H/HeJ X C57BL/6J )F2
The purpose of this experiment was to determine the expression traits in animals from F2 intercross of inbred strains C57BL/6J, C3H/HeJ. (N=309, 164 males and 145 females). Liver from 302 F2 female and male mice were generated by intercrossing F1 mice. Mice were fed chow diet containing 4% fat (Rals...
ORGANISM(S): Mus musculus 
2009-08-09 | E-GEOD-11338 | biostudies-arrayexpress
TranscriptomicsExpression profiling of Muscle tissue from C57BL/6J X C3H/HeJ)F2 and (C3H/HeJ X C57BL/6J)F2
The purpose of this experiment was to determine the expression traits in animals from F2 intercross of inbred strains C57BL/6J, C3H/HeJ. (N=309, 164 males and 145 females). Muscle from 285 F2 female and male mice were generated by intercrossing F1 mice. Mice were fed chow diet containing 4% fat (Ral...
ORGANISM(S): Mus musculus 
2009-08-09 | E-GEOD-12795 | biostudies-arrayexpress
TranscriptomicsExpression profiling of Brain tissue from C57BL/6J X C3H/HeJ)F2 and (C3H/HeJ X C57BL/6J)F2
The purpose of this experiment was to determine the expression traits in animals from F2 intercross of inbred strains C57BL/6J, C3H/HeJ. (N=309, 164 males and 145 females). Brain from 292 F2 female and male mice were generated by intercrossing F1 mice. Mice were fed chow diet containing 4% fat (Rals...
ORGANISM(S): Mus musculus 
2009-08-09 | E-GEOD-12798 | biostudies-arrayexpress
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