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MetabolomicsCharacterization of active peptides derived from three leeches and comparison of their anti-thrombotic mechanisms using the tail vein thrombosis model in mice and metabonomics

BACKGROUND AND AIMS: The increasing incidence of cardiovascular diseases has created an urgent need for safe and effective anti-thrombotic agents. Leech, as a traditional Chinese medicine, has the effect of promoting blood circulation and removing blood stasis, but its real mater...

2024-01-18 | MTBLS9306 | MetaboLights
ProteomicsPeptide codes for organ-selective mRNA delivery
Organ-selective delivery of messenger RNA (mRNA) is critical for fulfilling the therapeutic potential of mRNA-based gene and protein replacement technologies. Despite clinical advances in hepatic delivery of mRNA using lipid nanoparticles (LNPs), strategies for extrahepatic organ-selective mRNA deli...
ORGANISM(S): Mus Musculus 
2023-07-20 | PXD043932 |
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