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UnknownCryo-EM structure of the β-1,3-glucan synthase FKS1-Rho1 complex.
Not available
S-EPMC11871024 | biostudies-literature
ProteomicsSerum-based proteomics reveals lipid metabolic and immunoregulatory 、dysregulation in cervical artery dissection with stroke
Cervical artery dissection (CAD) is an important causal factor for stroke in young and middle-aged individuals and presents a great burden to the individual stroke victim. However, the pathophysiological mechanisms underlying CAD remain unknown. Here, an isobaric tagging for relative and absolute qu...
ORGANISM(S): Homo Sapiens 
2020-01-30 | PXD017340 |
ProteomicsComparison of cerebrospinal fluid proteomics between Demyelinating disease and non-inflammatory neurological controls
Demyelinating disease is a disease of the nervous system in which the nerve demyelinating is the main or primary lesion, and the axon, cell body and glia are relatively lightly damaged. It can occur in the central nervous system or the peripheral nervous system. The demyelinating diseases of central...
ORGANISM(S): Homo Sapiens 
2020-12-09 | PXD023027 |
ProteomicsInterorgan communication in the neurogenic heterotopic ossification: focusing on the role of brain-derived extracellular vesicles
Brain-derived extracellular vesicles participate in inter-organ communication after traumatic brain injury by transporting pathogens to initiate secondary injury. Inflammasome related proteins encapsulated in brain-derived extracellular vesicles are capable of crossing the blood-brain barrier to rea...
ORGANISM(S): Rattus Rattus 
2023-11-02 | PXD046626 |
ProteomicsRNF25-Mediated NF-κB Activation Drives Anti-Apoptosis and Therapy Resistance in Cancer
Dysregulation of the NF-κB pathway is frequently observed in cancers, where it contributes to therapy resistance by inhibiting apoptosis. Mass spectrometry (MS)-based proteomics were employed to identify factors associated with the anti-apoptotic process. We identify RNF25, an E3 ubiquitin ligase, a...
ORGANISM(S): Homo Sapiens 
2025-03-05 | PXD061521 |
ProteomicsThe subcortical maternal complex modulates the cell cycle during early mammalian embryogenesis via 14-3-3
The subcortical maternal complex (SCMC) is essential for the maintenance of female fertility in mammals. Most pathogenic mutations in SCMC-encoding genes result in female reproductive failure characterized by early embryonic arrest. Assembled in oocytes, the SCMC maintains the normal cleavage of ear...
ORGANISM(S): Mus Musculus Spodoptera Frugiperda 
2024-09-03 | PXD055498 |
ProteomicsAn essential maternal PADI6-UHRF1-UBE2D (MPU) complex regulates protein ubiquitination during oocyte maturation and embryogenesis
100 WT or Padi6Null MII oocytes for MS samples from three independent experiments and IP samples in 500 MII oocytes from one experiment were used for Mass spectrometry analysis.
ORGANISM(S): Mus Musculus 
2025-01-25 | PXD060230 |
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