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Heterosis is a fundamental biological phenomenon characterized by the superior performance of a hybrid over its parents in many traits, but the underlying molecular basis remains elusive. To investigate whether DNA methylation plays a role in heterosis, we compared at single base-pair resolution th...
ORGANISM(S): Arabidopsis thaliana 
In this project we discovered that CAP not only reduces joint swelling in arthritic model mice but also exhibits anti-inflammatory and antiproliferative effects on fibroblast-like synoviocytes (FLS). By synthesizing alkyne-tagged CAP probes and employing activity-based protein profiling (ABPP), we i...
ORGANISM(S): Homo Sapiens 
2024-11-07 | PXD057639 |
In this project we discovered that CAP not only reduces joint swelling in arthritic model mice but also exhibits anti-inflammatory and antiproliferative effects on fibroblast-like synoviocytes (FLS). By synthesizing alkyne-tagged CAP probes and employing activity-based protein profiling (ABPP), we i...
ORGANISM(S): Homo Sapiens 
2024-11-12 | PXD057819 |
Metabolome profile is an unexploited factor impacting the target efficacy and safety of nanomedicines by manipulating the formation of protein corona, and provide a novel way to develop personalized nanomedicines by harnessing disease-related metabolites.
ORGANISM(S): Homo Sapiens Mus Musculus Bos Taurus 
2023-03-24 | PXD041073 |
Heterosis is a fundamental biological phenomenon characterized by the superior performance of a hybrid over its parents in many traits, but the underlying molecular basis remains elusive. To investigate whether DNA methylation plays a role in heterosis, we compared at single base-pair resolution th...
ORGANISM(S): Arabidopsis thaliana 
Heterosis is a fundamental biological phenomenon characterized by the superior performance of a hybrid over its parents in many traits, but the underlying molecular basis remains elusive. To investigate whether DNA methylation plays a role in heterosis, we compared at single base-pair resolution th...
ORGANISM(S): Arabidopsis thaliana 
FAR-RED ELONGATED HYPOCOTYL 3 (FHY3) and its homolog FAR-RED IMPAIRED RESPONSE 1 (FAR1) are two transposase-derived transcription factors initially identified as the key components in phytochrome A signaling and recently shown to function in the circadian clock. However, whether FHY3 and FAR1 are in...
ORGANISM(S): Arabidopsis thaliana 
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