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MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
TranscriptomicsAffymetrix SNP array data for metastatic melanoma specimens
Comparison between the copy number of differentially methylated sites between lymph node metastasis from melanoma patients with good prognosis and melanoma brain metastasis. All samples are taken from different patients, and were established as cell lines in the John Wayne Cancer Institute. Sixteen ...
ORGANISM(S): Homo sapiens 
2013-09-19 | E-GEOD-44019 | biostudies-arrayexpress
TranscriptomicsEvolutionary Diversification of Duplicated Genes; Experiment L, K
This study measured the rates at which duplicated genes in the Daphnia pulex genome diverge in function, based on significant differences in their gene expression when paralogs of various ages were tested across 8 to 12 contrasting conditions. The conditions were designated A to L. The number and d...
ORGANISM(S): Daphnia pulex 
2011-02-01 | E-GEOD-25851 | biostudies-arrayexpress
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS390 | MetaboLights
UnknownDNA variants in CACNA1C modify Parkinson disease risk only when vitamin D level is deficient.
Not available
S-EPMC4830205 | biostudies-literature
TranscriptomicsAffymetrix expression array data for melanoma progression to the brain
Melanoma is one of the most aggressive and treatment-resistant cancers. It represents the most life-threatening neoplasm of the skin, and its incidence has been increasing for the last three decades. Melanoma evolves from the local transformation of melanocytes to primary tumors, which can metastasi...
ORGANISM(S): Homo sapiens 
2013-09-19 | E-GEOD-44660 | biostudies-arrayexpress
UnknownUsing synthetic biology to distinguish and overcome regulatory and functional barriers related to nitrogen fixation.
Not available
S-EPMC3723869 | biostudies-literature
UnknownAge- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.
Not available
S-EPMC5019754 | biostudies-literature
UnknownA bioengineered probiotic for the oral delivery of a peptide Kv1.3 channel blocker to treat rheumatoid arthritis.
Not available
S-EPMC9926172 | biostudies-literature
TranscriptomicsHOXA13 Chromatin Immunoprecipitation on human HG18 Nimblegen 2 array promoter set
HOXA13 Binding sites were located genome wide in primary human foreskin fibroblasts Tiled promoters with a probe per 100bp of refseq known genes 3kb upstream and 700 bp downstream of transcriptional start
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-9922 | biostudies-arrayexpress
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