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Therapeutic reduction of rad23a extends lifespan and mitigates pathology in TDP-43 mice. Xueshui Guo, Ravindra Prajapati, Jiyeon Chun, Insuk Byun, Kamil K Gebis, Yi-Zhi Wang, Karen Ling, Casey Dalton, Jeff Blair, Anahid Hamidianjahromi, Jeffrey N. Savas, Min Jae Lee, Jemeen Sreedharan, Robert Kalb
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-07-12 | MSV000095320 | MassIVE

BACKGROUND: One-third of inflammatory bowel disease (IBD) patients show no response to infliximab (IFX) induction therapy, and approximately half of patients responding become unresponsive over time. Thus, identification of potential treatment response biomarkers are of great cl...

2022-01-13 | MTBLS239 | MetaboLights
The study examines plasma metabolic profiles of patients with chronic obstructive pulmonary disease (COPD) to prove whether the disease influences metabolism at rest and after endurance training. This is based on the hypothesis that metabolome levels should reflect impaired skeletal muscle bioenerge...
2017-03-10 | MTBLS249 | MetaboLights
This study employs spectroscopy-based metabolic profiling of fecal extracts from healthy subjects and patients with active or inactive ulcerative colitis (UC) and Crohn's disease (CD) to substantiate the potential use of spectroscopy as a non-invasive diagnostic tool and to characterize the fecal me...
2017-02-07 | MTBLS237 | MetaboLights
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