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MetabolomicsSalmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence

Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermediates. The effects on...

2024-05-22 | MTBLS2347 | MetaboLights
MetabolomicsMetabolomics and Proteomics Reveal the Inhibitory Effect of Lactobacillus crispatus on Cervical Cancer Cells
Cervical cancer remains a significant global health issue due to its high morbidity and mortality rates. Recently, Lactobacillus crispatus has been recognized for its crucial role in maintaining cervical health. While some studies have explored the use of L. crispatus to mitigate cervical cancer, th...
2024-09-05 | MTBLS10498 | MetaboLights
UnknownDiosbulbin C, a novel active ingredient in Dioscorea bulbifera L. extract, inhibits lung cancer cell proliferation by inducing G0/G1 phase cell cycle arrest.
Not available
S-EPMC10694954 | biostudies-literature
UnknownInduction, Proliferation, Regeneration and Kinsenoside and Flavonoid Content Analysis of the Anoectochilus roxburghii (Wall.) Lindl Protocorm-like Body.
Not available
S-EPMC9570929 | biostudies-literature
TranscriptomicsReal-time quantitative PCR analysis of mouse RAW264.7 macrophages
Mouse RAW264.7 macrophages were treated with LPS, IFNb, poly(rI:rC), poly(dA:dT), VSV, HSV, Sendai virus. Genes identified by Human Innate Immunity Interactome for type I Interferon (HI5) were examined for expression. qPCR gene expression profiling. RAW264.7 macrophages were used and treated separat...
ORGANISM(S): Mus musculus 
2011-09-08 | E-GEOD-31790 | biostudies-arrayexpress
UnknownBTN3A1 expressed in cervical cancer cells promotes Vγ9Vδ2 T cells exhaustion through upregulating transcription factors NR4A2/3 downstream of TCR signaling.
Not available
S-EPMC11439235 | biostudies-literature
UnknownCo-Self-Assembled Interface Engineering Assisted for Bend-Resistant and Efficient Flexible Perovskite Solar Cells.
Not available
S-EPMC12806289 | biostudies-literature
UnknownStructural investigation of pathogenic RFC1 AAGGG pentanucleotide repeats reveals a role of G-quadruplex in dysregulated gene expression in CANVAS.
Not available
S-EPMC10954463 | biostudies-literature
UnknownStructural Insights into an Antiparallel Chair-Type G-Quadruplex From the Intron of NOP56 Oncogene.
Not available
S-EPMC12021085 | biostudies-literature
UnknownExcessive autophagic degradation of MYLK3 causes sunitinib-induced cardiotoxicity.
Not available
S-EPMC12758171 | biostudies-literature
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