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UnknownMolecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial.
Not available
S-EPMC4356709 | biostudies-literature
UnknownSRSF1 promotes the inclusion of exon 3 of SRA1 and the invasion of hepatocellular carcinoma cells by interacting with exon 3 of SRA1pre-mRNA.
Not available
S-EPMC8134443 | biostudies-literature
ProteomicsDistinct amyloid fibril structures formed by ALS-causing SOD1 mutants G93A and D101N
We expressed and purified recombinant full-length wild-type human SOD1 and its G93A and D101N variants in Expi293F cells where the initiating Met was removed and the N-terminus at Ala1 was acetylated, and identified N-terminal acetylation of the mammalian cell–purified G93A , D101N , and wild-type S...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD066116 | Pride
Amyotrophic lateral sclerosis (als)  sod1 mutants  amyloid fibrils  cryo-em structure  toxicity. 
UnknownSilencing of the lncRNA H19 enhances sensitivity to X-ray and carbon-ions through the miR-130a-3p /WNK3 signaling axis in NSCLC cells.
Not available
S-EPMC8642868 | biostudies-literature
UnknownTruncated SCRIB isoform promotes breast cancer metastasis through HNRNP A1 mediated exon 16 skipping.
Not available
S-EPMC10618471 | biostudies-literature
UnknownSTARD4 suppresses tumorigenesis and attenuates enzalutamide resistance via lipid metabolic reprogramming and AR stabilization in prostate cancer.
Not available
S-EPMC12699821 | biostudies-literature
ProteomicsTemporal Proteomic and Lipidomic Profiles of Cerulein-Induced Acute Pancreatitis Reveals Novel Insights for Metabolic Alterations in the Disease Pathogenesis
The pathophysiological mechanisms of acute pancreatitis (AP) are complex and have remained a mystery to date, but metabolism is gradually recognized as an important driver of AP onset and development. We used a cerulein-induced AP mouse model to conduct LC-MS/MS based time-course proteomics and lipi...
ORGANISM(S): Mus Musculus 
2022-12-06 | PXD038567 |
ProteomicsCharacterization of kidney-specific and site-specific N-glycosylation signatures of isolated uromodulin from human urine
Uromodulin (Umod, Tamm–Horsfall protein), as the most abundant urinary N-glycoprotein exclusively produced by the kidney, can form filaments to antagonize the adhesion of uropathogens. However, the kidney-specific and site-specific N-glycosylation signatures of this glycoprotein remain poorly unders...
ORGANISM(S): Homo Sapiens 
2023-05-11 | PXD041640 |
UnknownSelection criteria for large core trials: rationale for the ANGEL-ASPECT study design.
Not available
S-EPMC8785010 | biostudies-literature
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