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De novo synthesized protein DARPin F10 can target HDAC6 ZnF domain, and inhibits Influenza A virus and ZIKA virus infection. Our data shows it interferes with the virus uncoating step. To exclude the possibility that F10 upregulates interferon pathways, we checked the transcription of the cell
ORGANISM(S): Homo sapiens 
THP-1 cells were infected by IAV virus strain X31 with a MOI=10, and cells were collected at 3 timepoints:0 hr, 24 hr and 48 hr post-infection. Each timepoint has 3 biological replicates.
ORGANISM(S): Homo sapiens 
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