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GenomicGWAS of Preterm Birth

Preterm birth (PTB, born before 37 weeks of gestation) is a leading cause of neonatal mortality and post-natal morbidity. PTB affects one in nine all live births in the U.S. Notably, the highest rate of PTB occurs among African Americans (one in six). PTB is a complex trait, likely determined by ...

phs000332 | dbGaP
UnknownImmune checkpoint inhibitor-related gastrointestinal toxicity in patients with malignancy involving the luminal gastrointestinal tract and its impact on cancer outcomes.
Not available
S-EPMC9399574 | biostudies-literature
UnknownPatient HLA Germline Variation and Transplant Survivorship.
Not available
S-EPMC6097831 | biostudies-literature
UnknownClearance of Somatic Mutations at Remission and the Risk of Relapse in Acute Myeloid Leukemia.
Not available
S-EPMC6008108 | biostudies-literature
TranscriptomicsPseudomonas aeruginosa two-component regulator BfmR controls bacteriophage lysis and DNA release during biofilm development through PhdA
Biofilms are surface-adhered bacterial communities encased in an extracellular matrix composed of polysaccharides, proteins, and extracelluar (e)DNA, with eDNA being required for the formation and integrity of biofilms. Here we demonstrate that the spatial and temporal release of eDNA is regulated b...
ORGANISM(S): Pseudomonas aeruginosa 
2011-06-01 | E-GEOD-28953 | biostudies-arrayexpress
UnknownT Cells Genetically Modified to Express an Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor Cause Remissions of Poor-Prognosis Relapsed Multiple Myeloma.
Not available
S-EPMC6067798 | biostudies-literature
GenomicsThe complete methylome of hematopoietic stem cells and their immediate progeny
Hematopoietic stem cells (HSCs) constitute a rare cell population in bone-marrow and are capable of live-long self-renewal and production of all mature blood cell types. Cell differentiation processes are governed by epigenetic mechanisms whose study during early differentiation steps will provide i...
ORGANISM(S): Mus musculus 
2014-08-25 | E-GEOD-52709 | biostudies-arrayexpress
TranscriptomicsCD109 plays a role in osteoclastogenesis.
The primary aim of this project was to identify novel factors, in particular the cell-surface protein CD109, which regulate osteoclastogenesis. Microarray analysis was performed comparing two pre-osteoclast cell lines generated from the RAW 264.7 osteoclast cell line: one that has the capacity to fu...
ORGANISM(S): Mus musculus 
2013-01-29 | E-GEOD-43811 | biostudies-arrayexpress
UnknownResponse envelope analysis for quantitative evaluation of drug combinations.
Not available
S-EPMC7963081 | biostudies-literature
TranscriptomicsMicrocolony formation by the opportunistic pathogen Pseudomonas aeruginosa requires pyruvate and pyruvate fermentation.
A hallmark of the biofilm architecture is the presence of microcolonies. However, little is known about the underlying mechanisms governing microcolony formation. In the human pathogen Pseudomonas aeruginosa, microcolony formation is dependent on the two-component regulator MifR, with mifR mutant bi...
ORGANISM(S): Pseudomonas aeruginosa 
2012-04-30 | E-GEOD-35286 | biostudies-arrayexpress
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