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TranscriptomicsPseudomonas aeruginosa two-component regulator BfmR controls bacteriophage lysis and DNA release during biofilm development through PhdA
Biofilms are surface-adhered bacterial communities encased in an extracellular matrix composed of polysaccharides, proteins, and extracelluar (e)DNA, with eDNA being required for the formation and integrity of biofilms. Here we demonstrate that the spatial and temporal release of eDNA is regulated b...
ORGANISM(S): Pseudomonas aeruginosa 
2011-06-01 | E-GEOD-28953 | biostudies-arrayexpress
UnknownActivating NOTCH1 Mutations Define a Distinct Subgroup of Patients With Adenoid Cystic Carcinoma Who Have Poor Prognosis, Propensity to Bone and Liver Metastasis, and Potential Responsiveness to Notch1 Inhibitors.
Not available
S-EPMC5456373 | biostudies-literature
UnknownGenetic analysis and natural history of Parkinson's disease due to the LRRK2 G2019S variant.
Not available
S-EPMC11146432 | biostudies-literature
MetabolomicsHuman Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors including social communication and stereotypies. In addition to genetic risks, the gut microbiome differs between typically-developing (TD) and ASD individuals, though it remains unclear whether the microbiome contrib...
2019-07-04 | MTBLS726 | MetaboLights
MetabolomicsNMR based metabolomics study of Y2 receptor activation by neuropeptide Y in the SK-N-BE2 human neuroblastoma cell line
Neuropeptide Y (NPY) and its Y2 receptors (Y2R) play an important role in regulating growth of various tumors and are highly expressed in human neuroblastoma brain tumors. Cell lines derived from neuroblastoma brain tumors provide a good model to study the consequences of NPY activation of Y2R in tu...
2014-10-01 | MTBLS104 | MetaboLights
UnknownBrief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti-Interferon-γ Antibody, in Patients With Discoid Lupus Erythematosus.
Not available
S-EPMC5434930 | biostudies-literature
UnknownHuman papillomavirus type 16 (HPV-16) genomes integrated in head and neck cancers and in HPV-16-immortalized human keratinocyte clones express chimeric virus-cell mRNAs similar to those found in cervical cancers.
Not available
S-EPMC3028875 | biostudies-literature
ProteomicsGenome-wide screens identify SEL1L as an intracellular rheostat controlling collagen turnover
In-gel proteomics to identify affinity purified proteins
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD048563 | Pride
Sel1l 
UnknownAssessing variants of uncertain significance implicated in hearing loss using a comprehensive deafness proteome.
Not available
S-EPMC10182131 | biostudies-literature
UnknownAlpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson's models.
Not available
S-EPMC6123262 | biostudies-literature
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