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GenomicsDual Functions of TAF7L in Adipocyte Differentiation
The diverse transcriptional mechanisms governing cellular differentiation and development of mammalian tissue remains poorly understood. Here we report that TAF7L, a paralogue of TFIID subunit TAF7, is enriched in adipocytes and mouse white fat tissue (WAT). Depletion of TAF7L reduced adipocyte-spec...
ORGANISM(S): Mus musculus 
2013-01-07 | E-GEOD-41937 | biostudies-arrayexpress
Genomicsmerged_dataset - samples
This dataset contains merged data from the 22 Hodgkin lymphoma and 5 reactive lymph node samples, including count data and cell cluster assignments.
EGAD00001006221 | EGA
Genomicsena-DATASET-BCCA-11-12-2019-18:47:10:446-1110 - samples
Single-cell gene expression was profiled for 22 Hodgkin lymphoma tumors and 5 reactive lymph nodes (2 replicates were performed for RLN-1). Library preparation was performed with the 10x Chromium platform (3' version 2 assay). Sequencing was performed on an Illumina NextSeq. The BAM files were gener...
EGAD00001005739 | EGA
GenomicsSingle-cell RNA sequencing of 22 Hodgkin lymphoma tumors and 5 reactive lymph nodes
Hodgkin lymphoma (HL) is characterized by an extensively dominant tumor microenvironment (TME) composed of different types of non-cancerous immune cells with rare malignant cells. Characterization of the cellular components and their spatial relationship is crucial to understanding crosstalk and the...
EGAS00001004085 | EGA
UnknownTau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.
Not available
S-EPMC8857049 | biostudies-literature
UnknownHuman placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease.
Not available
S-EPMC8650129 | biostudies-literature
UnknownBi-allelic GOT2 Mutations Cause a Treatable Malate-Aspartate Shuttle-Related Encephalopathy.
Not available
S-EPMC6732527 | biostudies-literature
MetabolomicsProtein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights
UnknownMulti-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.
Not available
S-EPMC12330429 | biostudies-literature
UnknownRecurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections.
Not available
S-EPMC3738837 | biostudies-literature
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