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Here, we conducted an tandem mass tag (TMT)-based proteomics analysis of apple fruit development over five growth stages. Our objective was to gain a global overview of the dynamics of apple fruit development and identify key regulatory networks and proteins that contribute to fruit development and ...
ORGANISM(S): Malus domestica 
2016-10-13 | PXD004568 | Pride
Although the inhibitor of apoptosis protein-like protein-2 (ILP-2) is regarded as a novel growth enhancer for breast cancer, its mechanism on breast cancer cell growth remains elusive and requires further study. In this study, isobaric tags were applied for relative and absolute quantification (iTRA...
ORGANISM(S): Homo Sapiens 
2019-02-25 | PXD012848 |
Phenotypic plasticity has emerged as an important mechanism of therapy resistance in cancers, yet the underlying molecular mechanisms remain unclear. Using an established breast cancer cellular model for endocrine resistance, we show that hormone resistance is associated with enhanced phenotypic pla...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-05-24 | MSV000083857 | MassIVE
To assess the efficacy and safety of BYHWD combined with guideline-guided pharmacotherapy in patients with IHF and explore the biological mechanism by which BYHWD exerts its efficacy.
ORGANISM(S): Homo Sapiens 
2021-11-17 | PXD029771 |
Macrophages, locating in essentially all tissues, are critical for innate immune responses and involved in the tissue homeostasis. Distinct macrophages populations in different tissues exhibited diverse gene expressions and biological processes. Previous studies have accessed the molecular signature...
ORGANISM(S): Mus Musculus 
the data of validation experiments for pan-sarcoma projects
ORGANISM(S): Homo Sapiens 
2024-01-03 | PXD047429 |
we establish a 272 Chinese STS patients cohort containing 12 sarcoma subtypes, well-differentiated liposarcoma (WDLPS), myxoid liposarcoma (MLPS), dedifferentiated liposarcoma (DDLPS), angiosarcoma (AS), undifferentiated sarcoma (UPS), myxofibrosarcoma (MFS), other fibroblastic/myofibroblastic tumor...
ORGANISM(S): Homo Sapiens 
2024-01-03 | PXD047297 |
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