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This data set was used to study FLT3 wild type and mutants in childhood AML samples from the Pediatric Oncology Group Study 9421. Abstract: Fms-like tyrosine kinase 3 (FLT3) mutations are associated with unfavorable outcomes in children with acute myeloid leukemia (AML). We used DNA microarrays to i...
ORGANISM(S): Homo sapiens 
In plants, fatty acids are de novo synthesized predominantly in plastids fromacetyl-CoA. Although fatty acid biosynthesis has been biochemically well-studied, little isknown about the regulatory mechanisms of the pathway. Here, we show that overexpressionof the Arabidopsis (Arabidopsis thaliana) LEA...
ORGANISM(S): Arabidopsis thaliana 
Ulcerative colitis (UC) is a chronic recurrent inflammatory bowel disease, which is characterized by intestinal microbiota dysbiosis, intestinal barrier and mucosal immune dysfunction. Given the limited effect of biological agents for UC, there is an urgent need to develop more effective pharmacolog...
2026-08-30 | MTBLS15475 | MetaboLights
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