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UnknownPercolation Phase Transition of Surface Air Temperature Networks: A new test bed for El Nino/La Nina simulations.
Not available
S-EPMC5559492 | biostudies-literature
TranscriptomicsComparative genomics using microarrays studied in Metarhizium anisopliae 2575 and 324
The entomopathogen Metarhizium anisopliae contains strains with wide host ranges and specialist strains adapted to particular hosts. Patterns of gene duplication, divergence and deletion in three generalist and three specialist strains were investigated by heterologous hybridization of genomic DNA t...
ORGANISM(S): Metarhizium anisopliae 
2010-05-16 | E-GEOD-14846 | biostudies-arrayexpress
TranscriptomicsProteomic and transcriptomic responses to thiamethoxam in the Sweetpotato whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae)
We investigated the transcriptional response to thiamethoxam in the Bemisia tabaci using Illumina sequencing technology. A total of 1,338 genes were differently expressed in the thiamethoxam-resistant whiteflies. All the B biotype whiteflies were maintained on cabbage. The susceptible strain (TH-S)...
ORGANISM(S): Bemisia tabaci 
2013-07-15 | E-GEOD-42102 | biostudies-arrayexpress
TranscriptomicsConjugated linoleic acid activates AMPK and reduces adiposity more effectively when used with metformin
Trans-10, cis-12 conjugated linoleic acid (t10c12 CLA) causes dramatic reductions in white adipose tissue in mice but has had limited effectiveness in humans. Determination of the signaling pathways involved may lead to better regulation of adiposity. T10c12 CLA was found to activate AMP-activating...
ORGANISM(S): Mus musculus 
2009-11-01 | E-GEOD-14888 | biostudies-arrayexpress
TranscriptomicsMapping of hns sites in Typhimurium 14028 using a tiling oligo array
The NimbleGen array contains 387,000 46~50-mer oligos, including 377,230 salmonella probes whose sequences only hit genome once. The probes were designed based on Salmonella typhimurium LT2 (NC_003197) genome, with a moving window of about 12 bases. Raw intensities were normalized by the median inte...
ORGANISM(S): Salmonella 
2010-07-01 | E-GEOD-4879 | biostudies-arrayexpress
TranscriptomicsIdentification of a hepatocyte stem cell and its niche in liver homeostasis
Summary: RNAseq analysis of Axin2+ hepatocyte stem cells versus Axin2- mature hepatocytes shows that Axin2+ cells have a distinct gene expression profile compared to Axin2- hepatocytes. Methods: Hepatocytes were isolated from 8 week old Axin2rtTA;TetO-H2B-GFP mice (n = 3) given doxycycline in drinki...
ORGANISM(S): Mus musculus 
2015-08-07 | E-GEOD-68806 | biostudies-arrayexpress
TranscriptomicsAlzheimer's Disease Dataset
FK506 binding protein 51kDa (FKBP51/FKBP5) is part of a mature heat shock protein 90kDa (Hsp90) chaperone complex that preserves tau. Microarray analysis of human brains reveal that FKBP51 gene expression selectively increased with age and Alzheimer's disease, which correlated with demethylation of ...
ORGANISM(S): Homo sapiens 
2014-04-21 | E-GEOD-48350 | biostudies-arrayexpress
MetabolomicsFFAR4-mediated IL-6 release from islet macrophages promotes insulin secretion and is compromised in type-2 diabetes

The function of islet macrophages is poorly understood. They promote glucose-stimulated insulin secretion (GSIS) in lean mice, however, the underlying mechanism has remained unclear. We show that activation of the free fatty acid receptor FFAR4 on islet macrophages leads to interleukin-6 (IL-6) r...

2026-08-19 | MTBLS12317 | MetaboLights
TranscriptomicsFree fatty acids and TNF-alpha in HepG2 cell culture
The regulation of complex cellular activities in palmitate treated HepG2 cells, and the ensuing cytotoxic phenotype, involves cooperative interactions between genes. While previous approaches have largely focused on identifying individual target genes, elucidating interacting genes has thus far rema...
ORGANISM(S): Homo sapiens 
2012-05-01 | E-GEOD-26885 | biostudies-arrayexpress
UnknownCombined -omics framework reveals how ant symbionts benefit the Neotropical ant-plant Tococa quadrialata at different levels.
Not available
S-EPMC9579026 | biostudies-literature
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