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ProteomicsTMT-based Quantitative analysis of Isatis indigotica leaf tissue
By conducting TMT labeled quantitative proteomic analysis on the leaves of Radix Isatidis under different stress conditions, the potential biological mechanisms of the impact of abiotic stress on the quality of Radix Isatidis were studied.
ORGANISM(S): Isatis Tinctoria 
2024-11-25 | PXD058215 |
ProteomicsDiscovery of Novel MLKL PROTAC Degrader for the Treatment of Hepatocellular Carcinoma via Promoting Parthanatos
Chen et al. discovered a highly potent and selective MLKL-targeted PROTAC C116 that effectively induces MLKL degradation and promotes parthanatos in HCC cells. More significantly, C116 was able to induce in vivo MLKL degradation and exerts anti-tumor activities in an orthotopic HCC tumor model, posi...
ORGANISM(S): Mus Musculus 
2025-10-14 | PXD069462 |
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