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Statins are among the most frequently prescribed drugs because of their efficacy and low toxicity in treating hypercholesterolemia. Recently, statins have been reported to inhibit the proliferative activity of cancer cells, especially those with *TP53* mutations. Since *TP53* mutations occur in ...
ORGANISM(S): Homo sapiens 
Mice developed ovarian tumors after Arid1a and Pten double knockout. Gene expression profiles of 5 such ovarian tumors were compared with those of 4 normal ovaries. The differentially expressed genes were then used to investigate the similarity between the mouse ovarian tumors and major subtypes of ...
ORGANISM(S): Mus musculus 
Wild type, elg1d, pol30f, and pol30f elg1d cells were arrested in G1 and synchronously released in the presence of HU for 30 or 60 minutes. Genomic DNA was extracted, amplified, and hybridized to a whole genome tiling microarray. Replicated regions were identified as peaks that exhibit increased co...
ORGANISM(S): Saccharomyces cerevisiae 
There are remarkable disparities among patients of different races with prostate cancer; however, the mechanism underlying this difference remains unclear. Here, we present a comprehensive landscape of the transcriptome profiles of 14 primary prostate cancers and their paired normal counterparts fro...
ORGANISM(S): Homo sapiens 
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