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TranscriptomicsiCLIP of TDP-43
A stable HEK293 FlpIn T-Rex cells expressing TDP-43 with an N-terminal eGFP-tag was generated that allowed inducible physiological expression of the protein (Ling et al. 2010). Duplicate iCLIP experiments were performed using an antibody targeting eGFP (Abcam ab290). Crosslinked RNA-protein complexe...
ORGANISM(S): Homo sapiens 
2017-05-01 | E-MTAB-4733 | biostudies-arrayexpress
TranscriptomicsMonitoring of functional gene responses to ERD (enhanced reductive dechlorination) from four TCE-contaminated sites
A functional microarray targeting 24 genes involved in chlorinated solvent biodegradation pathways has been developed and used to monitor the gene diversity present in four trichloroethylene (TCE) contaminated sites under ERD (enhanced reductive dechlorination) treatment. The microarray format provi...
ORGANISM(S): groundwater metagenome 
2012-04-02 | E-GEOD-28606 | biostudies-arrayexpress
TranscriptomicsExpression profiling of T.rubrum treated with PH11B
T. rubrum was treated with PH11B,a potent eucaryotic fatty acid synthase inhibtor. A cDNA microarray was constructed from the expressed sequence tags (ESTs) of different developmental stages, and transcriptional profiles of the responses to PH11B were determined. Some class-specific and mechanism-i...
ORGANISM(S): Trichophyton rubrum 
2007-11-21 | E-GEOD-6336 | biostudies-arrayexpress
UnknownThe association between fat distribution and α1-acid glycoprotein levels among adult females in the United States.
Not available
S-EPMC11290176 | biostudies-literature
ProteomicsMass spectrometry based detergent-insoluble proteins of human cell lysates
The PXD project contains a project which aimed to identify protein evidences (missing proteins) from insoluble proteins from cell lysate by mass spectrometry. It involves the analysis of 3 human lung cell line and 3 liver cell lines,including the identification information and quantitative informa...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079997 | MassIVE
UnknownThe SETDB1-TRIM28 Complex Suppresses Antitumor Immunity.
Not available
S-EPMC8647838 | biostudies-literature
TranscriptomicsInositol requiring enzyme 1? augments angiogenesis for diabetic wound healing
The microarray analysis is to investigate the different expression profile of microRNAs in bone marrow-derived progenitor cells from type 2 diabetic mice and healthy control mice. microRNA expression profiles were compared between bone marrow-derived progenitor cells from either type 2 diabetic db/...
ORGANISM(S): Mus musculus 
2015-09-02 | E-GEOD-72616 | biostudies-arrayexpress
UnknownIn-utero co-exposure to toxic metals and micronutrients on childhood risk of overweight or obesity: new insight on micronutrients counteracting toxic metals.
Not available
S-EPMC9329205 | biostudies-literature
UnknownSpatial Transcriptomic Analysis of Ovarian Cancer Precursors Reveals Reactivation of IGFBP2 during Pathogenesis.
Not available
S-EPMC9808976 | biostudies-literature
Transcriptomics3'-end targeted sequencing of 6 control and 6 TDP-43 KD samples in HEK293
HEK293 FlpIn T-Rex cells were maintained in Dulbeccos Modified Eagle Medium (DMEM) with 10% fetal bovine serum (FBS), supplemented with 3 g/ml blasticidine and 50 g/ml zeocin. For the siRNA-induced knockdown of TDP-43, 20 nM of TDP-43 stealth siRNA was mixed with 10 L of RNAiMAX following the manufa...
ORGANISM(S): Homo sapiens 
2017-05-01 | E-MTAB-4732 | biostudies-arrayexpress
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