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RNA sequences are expected to be identical to their corresponding DNA sequences. Advances in technologies have enabled deep sequencing of nucleic acids that uncovered exceptions to the one-to-one relationship between DNA and RNA sequences. Previously in human cells, post-transcriptional RNA editin...
ORGANISM(S): Homo sapiens 
This dataset contains merged data from the 22 Hodgkin lymphoma and 5 reactive lymph node samples, including count data and cell cluster assignments.
Single-cell gene expression was profiled for 22 Hodgkin lymphoma tumors and 5 reactive lymph nodes (2 replicates were performed for RLN-1). Library preparation was performed with the 10x Chromium platform (3' version 2 assay). Sequencing was performed on an Illumina NextSeq. The BAM files were gener...
Hodgkin lymphoma (HL) is characterized by an extensively dominant tumor microenvironment (TME) composed of different types of non-cancerous immune cells with rare malignant cells. Characterization of the cellular components and their spatial relationship is crucial to understanding crosstalk and the...
Cell lysates were adjusted to 5% SDS, and 20 ugs was reduced with 10 mM DTT and alkylated with 25 mM iodoacetamide followed by digestion with 1:15 trypsin using an S-trap at 47 degC for 1 h. Lyophilized peptides were reconstituted at 0.5 ugs/uL, and a study pool QC sample was made by mixing equal vo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-12 | MSV000093088 | MassIVE
Lipomyces genome scale model based on the Lipomyces starkeyi NRRL-11557 genome. Published in: Genome-Scale Model Development and Genomic Sequencing of the Oleaginous Clade Lipomyces Frontiers in Bioengineering and Biotechnology Industrial Biotechnology Volume 12 - 2024 | doi: 10.3389/fbioe.2024.135...
2024-03-20 | MODEL2403190001 | BioModels
Early-life antibiotic exposure perturbs the intestinal microbiota, alters innate intestinal immunity, and accelerates type 1 diabetes development in the NOD mouse model. Here we found that maternal cecal microbiota transfer (CMT) to NOD mice with early-life antibiotic perturbation partially rescued ...
ORGANISM(S): Mus musculus 
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