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MetabolomicsDistinct metabolic profiling is correlated with bisexual flowers formation resulting from exogenous ethephon induction in melon (Cucumis melo L.)

Melon (Cucumis melo L.) is an agronomically important vegetable. Most cultivars of melon are andromonoecious and bisexual flowers only emerged from the leaf axil of lateral branches. However, the regulatory mechanism contributing to the occurrence of bisexual flowers were still obscure. ...

2022-03-10 | MTBLS2993 | MetaboLights
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unknown. Here, through a longitudinal analysis on 181 COPD individuals from two large cohorts involvi...

2023-06-12 | MTBLS5423 | MetaboLights
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Murine UPLC-MS/MS assays)

Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease (COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression remains unknown. Here we showed, through a longitudinal analysis on two cohorts involving four UK centers, that basel...

2023-06-12 | MTBLS6894 | MetaboLights
MetabolomicsThe effects of different rootstocks on aroma components, activities and genes expression of aroma-related enzymes in oriental melon fruit

Grafting is widely applied in the cultivation of melon. In this study, 'Qinmi No.1' [Cucumis melo L. (QG)] and 'Ribenxuesong' [Cucurbita maxima Duch. (RG)] were used as rootstocks for 'QingxinYangjiaocui' (Cucumis melo L.). The results showed that grafting with...

2023-11-21 | MTBLS8677 | MetaboLights
TranscriptomicsGenome-wide Gene Expression Profiling of Salinity Responsiveness in Rice
Abiotic stresses such as salinity are very important factors limiting rice growth and productivity around the world. Affymetrix rice genome array containing 48,564 japonica and 1,260 indica sequences was used to analyze the gene expression pattern of rice responsive to salinity stress, try to elucid...
ORGANISM(S): Oryza sativa 
2015-11-02 | E-GEOD-58603 | biostudies-arrayexpress
UnknownEfficacy and Tolerability of First-Line Cetuximab Plus Leucovorin, Fluorouracil, and Oxaliplatin (FOLFOX-4) Versus FOLFOX-4 in Patients With RAS Wild-Type Metastatic Colorectal Cancer: The Open-Label, Randomized, Phase III TAILOR Trial.
Not available
S-EPMC6324088 | biostudies-literature
TranscriptomicsOptimized siRNAs with a minimal off-target effect facilitate the screening of essential genes in cancer cells
siRNAs with dN are a promising and easy approach to characterize essential genes by minimizing the off-target effect in cancer cells. mRNA profiles of HCT 116 cells after the transfection of siRNAs or blank control by deep sequencing, using HiSeq 2000
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-62968 | biostudies-arrayexpress
ProteomicsQuantitative proteomic analysis of iron oxide nanoparticles toxicity in rats
Iron oxide nanoparticles (IONPs) are the first generation of nanomaterials approved by the Food and Drug Administration for use as imaging agents and for the treatment of iron deficiency in chronic kidney disease. However, several IONPs-based imaging agents have been withdrawn because of toxic effec...
ORGANISM(S): Rattus Norvegicus 
2022-08-11 | PXD035970 |
TranscriptomicsAnalysis the Ability of Producing Secondary Metabolites of Streptomyces bingchenggensis By The Genome Sequence and GeneChip DNA microarrays
Streptomyces bingchenggensis is a soil bacterium that produces a family of macrolide antibiotics, milbemycins, which is commercially important in crop protection, human and veterinary medicine. After the complete genome sequence, and annotation, for further development of our gene expression approac...
ORGANISM(S): Streptomyces bingchenggensis 
2011-09-19 | E-GEOD-32205 | biostudies-arrayexpress
ProteomicsIntegrative Proteomics Reveals Mitochondrial and Immune Signatures of MLH1 Exon 13 Deletion in Lynch Syndrome–Associated Colorectal Cancer
Background: Lynch syndrome is an inherited cancer predisposition caused by pathogenic variants in mismatch repair (MMR) genes. Large genomic rearrangements (LGRs) in MLH1 are often underestimated due to detection challenges. Functional analyses of specific variants such as MLH1 exon 13 deletion (MLH...
ORGANISM(S): Homo Sapiens 
2025-12-10 | PXD071799 |
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