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Molecular changes caused by metabolic reprogramming in ischemia and reperfusion cortex remain an unaddressed issue. Applying the quantitative proteomic and lactylproteomic analysis, we found that the molecular changes of ischemic brain tissues are quite different between ischemia and reperfusion sta...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD019323 | Pride
The details of Toll-like receptor (TLR) 4 signaling affects protein succinylation in intracerebral hemorrhage (ICH) brains remains completely unclear. In this study, we constructed mice ICH models to investigate the changes in ICH-associated brain protein succinylation with the treatment of TLR4 ant...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-03 | PXD025622 | Pride
Recent studies have demonstrated direct reprogramming of fibroblasts into a range of somatic cell types, but to date stem/progenitor cells have only been reprogrammed for the blood and neuronal lineages. We previously reported generation of induced hepatocyte-like (iHep) cells by transduction of Gat...
ORGANISM(S): Mus musculus 

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

A comprehensive comparison analysis of proteins in exosomes derived from S. aureus-infected (SA group) and normal MAC-T cells (C group) was performed using a shotgun proteomic by DIA approach.
ORGANISM(S): Bos Taurus 
2022-10-09 | PXD037220 |
Electroacupuncture Activated Local Sympathetic Noradrenergic Signaling to relieve synovitis and referred pain behaviors in KOA Rats
ORGANISM(S): Rattus Norvegicus 
2022-11-29 | PXD038461 |
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