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MetabolomicsMicrobiome and metabolome features in inflammatory bowel disease via multi-omics integration analyses across cohorts

The perturbations of the gut microbiota and metabolites are closely associated with the progression of inflammatory bowel disease (IBD). However, inconsistent findings across studies impede a comprehensive understanding of their roles in IBD and their potential as reliable diagnostic biomarkers. ...

2026-01-28 | MTBLS8713 | MetaboLights
MetabolomicsACAD8 deficiency promotes pathological cardiac hypertrophy in response to pressure overload by regulating histone isobutyrylation
Branched-chain amino acids play critical roles in cardiac physiology and diseases. Genetic deficiency in the valine catabolic enzyme ACAD8 is clinically associated with isobutyryl-CoA deregulation and cardiomyopathy in humans. To explore the mechanism underlying cardiac pathological hypertrophy in A...
2026-04-15 | MTBLS14207 | MetaboLights
ProteomicsQuantitative analysis of the antibacterial effect of cinnamaldehyde on Staphylococcus aureus based on TMT protein
TMT quantitative proteomics was used to analyze the changes of protein expression in MRSA under the action of CA, and the antibacterial mechanism of CA on MRSA was further revealed.
ORGANISM(S): Staphylococcus Aureus 
2024-08-14 | PXD054851 |
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