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DNA methylation plays a significant role in assuring cell identity, thus potentiating its application in molecular classification of cancers in respect of tissue origins or clinically and aetiologically distinct subtypes. In this study, we adapted our liquid hybridization capture-based bisulfite seq...
ORGANISM(S): Homo sapiens 
High levels of mitochondrial reactive oxygen species (mROS) are linked to cancer development, which is tightly controlled by electron transport chain (ETC). Targeting ETC represents a promising way of curing cancers. However, the epigenetic mechanisms governing ETC gene transcription to drive mROS p...
ORGANISM(S): Homo Sapiens 
2022-06-07 | PXD034400 |
Esophageal cancer (EC) is anaggressive cancer type without clinically relevant molecular subtypes defined, which hinders the development of effective strategies forEC treatment. Here, we reporteda large-scale, high-resolution massspectrometry-based proteomicand phosphoproteomics profiling of EC tumo...
ORGANISM(S): Trichuris Sp. Ex Homo Sapiens Jp-2011 
2021-07-05 | PXD021701 |
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