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UnknownAR-V7 and resistance to enzalutamide and abiraterone in prostate cancer.
Not available
S-EPMC4201502 | biostudies-literature
UnknownCircuit implementation of a four-dimensional topological insulator.
Not available
S-EPMC7217906 | biostudies-literature
UnknownTopologically enhanced harmonic generation in a nonlinear transmission line metamaterial.
Not available
S-EPMC6405745 | biostudies-literature
UnknownVortex states in an acoustic Weyl crystal with a topological lattice defect.
Not available
S-EPMC8209201 | biostudies-literature
UnknownImage reconstruction through a multimode fiber with a simple neural network architecture.
Not available
S-EPMC7806887 | biostudies-literature
TranscriptomicsThe Estrogen Receptor Co-Regulator Protein, Proline Glutamic Acid and Leucine Rich Protein 1 (PELP1) Mediates Estrogen Rapid Signaling and Neuroprotection in the Brain
We examined the role of PELP1 in E2-ER-mediated transcription in the hippocampus under conditions of GCI by perfroming global transcriptome analysis. E2-treated FLOX and PELP1 FBKO mice were subjected to GCI followed by 24 h reperfusion and the isolated RNA was utilized for RNA-seq analysis. Our res...
ORGANISM(S): Mus musculus 
2015-12-07 | E-GEOD-72136 | biostudies-arrayexpress
TranscriptomicsRNA-Seq analysis of prostate tumors with or without androgen receptor splice variant
Background. Androgen receptor splice variant-7 (AR-V7) is a truncated form of the androgen receptor protein which lacks the ligand-binding domain, the target of enzalutamide and abiraterone, but remains constitutively active as a transcription factor. We hypothesized that detection of AR-V7 in circ...
ORGANISM(S): Homo sapiens 
2014-09-03 | E-GEOD-56701 | biostudies-arrayexpress
TranscriptomicsAndrogen-Responsive microRNAs in mouse Sertoli Cells
Although decades of research have established that androgen is essential for spermatogenesis, androgen’s mechanism of action remains elusive. This is in part because only a few androgen-responsive genes have been definitively identified in the testis. Here, we report that microRNAs—small, noncoding ...
ORGANISM(S): Mus musculus 
2012-12-21 | E-GEOD-37679 | biostudies-arrayexpress
TranscriptomicsTrans. Profiling of Immortalized Melanocyte Cell Lines Identifies GPNMB as a Melanoblast-Expressed, MITF-Dependent Gene
Gene expression profiling of tissues derived from different genetic backgrounds can provide insight to potential phenotype-related changes in gene expression. We have compared wildtype C57BL/6 (melan-Ink4a) melanocyte cell gene expression to that of, “brown“ Tyrp1b/ b (melan-Ink4a-b) and “cho...
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-10163 | biostudies-arrayexpress
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