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MetabolomicsEnergy-stress-mediated AMPK activation inhibits ferroptosis

Energy stress depletes ATP and induces cell death. Here we identify an unexpected inhibitory role of energy stress on ferroptosis, a form of regulated cell death induced by iron-dependent lipid peroxidation. We found that ferroptotic cell death and lipid peroxidation can be inhibited by treatment...

2023-01-31 | MTBLS1399 | MetaboLights
UnknownEfficacy of the Combination Therapy of Intense Pulsed Light and Microneedling With a Postbiotic Formulation for Melasma.
Not available
S-EPMC12679679 | biostudies-literature
ProteomicsPD-L1 Mediated Immune Evasion in Triple Negative Breast Cancer Is Linked to the Loss of ZNF652
The intrinsic regulation of PD-L1 expression remains unclear. Here we report that ZNF652 is a potent transcription repressor of PD-L1. ZNF652 frequently loses heterozygosity (LOH) in various cancers. Higher LOH rate and lack of estrogen-inducible transcription lead to suppressed expression of ZNF652...
ORGANISM(S): Homo Sapiens 
2023-09-29 | PXD045945 |
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