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In this study, we used minimally invasive abdominal fat biopsies routinely performed in clinical practice, to obtain amyloid fibrils from living MM patient. Using cryo-electron microscopy (cryo-EM) and mass spectrometry (MS), we successfully determined the sequence and high-resolution structure of l...
ORGANISM(S): Homo sapiens (Human) 
2025-12-25 | PXD065426 | Pride
In this study, we used minimally invasive abdominal fat biopsies routinely performed in clinical practice, to obtain amyloid fibrils from living MM patient. Using cryo-electron microscopy (cryo-EM) and mass spectrometry (MS), we successfully determined the sequence and high-resolution structure of l...
ORGANISM(S): Homo sapiens (Human) 
2025-12-25 | PXD065428 | Pride
Biofilms formed by Shewanella oneidensis MR-1 are crucial for metal reduction, underpinning bioremediation and bioenergy applications, yet detailed structural insights into biofilm components remain limited. Here we show that MR-1 biofilms contain abundant filamentous networks, membrane vesicles, an...
ORGANISM(S): Shewanella oneidensis (strain MR-1) 
2026-09-07 | PXD075695 | Pride
Cryo-EM structure of patient-derived transthyretin amyloid fibrils from an abdominal fat biopsy.
ORGANISM(S): Homo sapiens (Human) 
2026-08-24 | PXD071259 | Pride
Cryo-EM structure of patient-derived transthyretin amyloid fibrils from an abdominal fat biopsy.
ORGANISM(S): Homo sapiens (Human) 
2026-08-24 | PXD071190 | Pride
Cryo-EM structure of patient-derived transthyretin amyloid fibrils from an abdominal fat biopsy.
ORGANISM(S): Homo sapiens (Human) 
2026-08-24 | PXD071096 | Pride
These are only the whole exome sequences
This is the complete dataset (exome and genome) for the EGAS00001000974 study.
Neurofibromatosis 1 is a hereditary syndrome characterized by the development of numerous benign neurofibromas, a small subset of which progress to malignant peripheral nerve sheath tumors (MPNSTs). To better understand the genetic basis for MPNSTs, we performed whole genome sequencing on four MPNST...
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