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ProteomicsPhosphoproteomics reveal that phosphorylation of MTDH by CDK5 inhibits protein synthesis in microglia
Our findings identified 335 phosphorylation sites on 234 proteins as potential CDK5 substrates in microglia based on the reported sequence motif
ORGANISM(S): Mus Musculus 
2024-03-08 | PXD050465 |
ProteomicsDIA-based quantitative proteomics reveals the protein regulatory networks of floral thermogenesis in Nelumbo nucifera
The flower chambers of sacred lotus (Nelumbo nucifera) can maintain a relatively stable temperature during anthesis despite the large environmental temperature fluctuations. However, the regulatory mechanism of floral thermogenesis remains largely unclear. To further understand the molecular basis o...
ORGANISM(S): Nelumbo Nucifera 
2021-02-20 | PXD024269 |
ProteomicsCleavage of CAD by caspase-3 determines the cancer cell fate during chemotherapy
Metabolic heterogeneity resulting from the intrinsic heterogeneity of human tumors has been shown to cause a myriad of adverse outcomes of tumor therapy, including resistance to chemotherapy, but the mechanisms inside remain largely unknown. Here, we found that the de novo pyrimidine synthesis pathw...
ORGANISM(S): Homo Sapiens 
2025-01-01 | PXD059365 |
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