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GenomicsGenome-wide analysis reveals positional-nucleosome-oriented binding pattern of pioneer factor FOXA1
By analysis of ChIP-exo of FOXA1 in LNCaP, we find that an astonishing genome-wide "well-positioned" configuration prevalently occurs between FOXA1 motif and the dyad of nucleosome. Here we performed ChIP-seq data of eight chromatin remodelers and found a higher occupancy of these remodel...
ORGANISM(S): Homo sapiens 
2016-08-01 | E-GEOD-72690 | biostudies-arrayexpress
GenomicsIntegrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this work is comprehensive analysis of target genes co-regulated by CREB1 and FoxA1 in prostate cancer cell models, tissues, and circulating tumor cells (CTCs). Expression of CREB1/...
ORGANISM(S): Homo sapiens 
2016-01-13 | E-GEOD-63034 | biostudies-arrayexpress
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