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MetabolomicsPolicosanol Alleviates Chronic Stress-Induced Growth Impairment via Gut Microbiota-Metabolite Interactions: Insights from 16S rRNA Sequencing and LC-MS Metabolomics

Background/Objectives: Policosanol, a bioactive compound derived from rice bran wax, has demonstrated potential for alleviatingshown potential in combating stress, yet its underlying mechanisms remain elusive. This study aimed to elucidate its role in mitigating chronic stress-induced growth impa...

2025-10-21 | MTBLS13189 | MetaboLights
ProteomicsThe role of Ptpn11E76K in MSC fate determination
MSCs expressing Ptpn11+/+ or Ptpn11E76K/+ were lysed for proteomic analysis. In brief, 0.5 μg of peptide mixture resolved in buffer A (0.1% formic acid) was loaded onto a 2‒cm self‒packed trap column using buffer A and separated on a 150 μm‒inner‒diameter column with a length of 15 cm over a 78‒min ...
ORGANISM(S): Mus Musculus 
2023-02-28 | PXD040487 |
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