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UnknownConcurrent V(D)J recombination and DNA end instability increase interchromosomal trans-rearrangements in ATM-deficient thymocytes.
Not available
S-EPMC3632137 | biostudies-literature
UnknownNear-tetraploid cancer cells show chromosome instability triggered by replication stress and exhibit enhanced invasiveness.
Not available
S-EPMC5998968 | biostudies-literature
GenomicsCharacterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization
Recent epigenomic studies have predicted thousands of potential enhancers in the human genome. However, there has not been systematic characterization of target promoters for these potential enhancers. Using H3K4me2 as a mark for active enhancers, we identified genome-wide enhancer-promoter interact...
ORGANISM(S): Homo sapiens 
2012-01-24 | E-GEOD-32677 | biostudies-arrayexpress
UnknownATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer.
Not available
S-EPMC10405061 | biostudies-literature
UnknownDual inhibition of EGFR and PI3Kinase signaling in EGFR amplified triple negative breast cancer cells induces apoptosis and reduces tumor growth.
Not available
S-EPMC12157506 | biostudies-literature
UnknownEGFR amplification and PI3K pathway mutations identify a subset of breast cancers that synergistically respond to EGFR and PI3K inhibition.
Not available
S-EPMC12714574 | biostudies-literature
UnknownEstrogenic Effect of Scoparia dulcis (Linn) Extract in Mice Uterus and In Silico Molecular Docking Studies of Certain Compounds with Human Estrogen Receptors.
Not available
S-EPMC7648873 | biostudies-literature
UnknownCharacterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization.
Not available
S-EPMC3292289 | biostudies-literature
UnknownSingle Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression.
Not available
S-EPMC6434407 | biostudies-literature
UnknownA multiplex preclinical model for adenoid cystic carcinoma of the salivary gland identifies regorafenib as a potential therapeutic drug.
Not available
S-EPMC5595986 | biostudies-literature
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