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Shlomi2011 - Warburg effect, metabolic model Using a genome-scale human metabolic network model accounting for stoichiometric and enzyme solvent capacity considerations, this model shows that the Warburg effect (a classical hallmark of cancer metabolism) is a direct consequence of...
2005-01-01 | MODEL1105100000 | BioModels
Tumor chemoresistance is often associated to high aerobic glycolysis rates and reduced oxidative phosphorylation by cancer cells, a phenomenon called the “Warburg effect”. Thus, a treatment reversing the Warburg effect could decrease tumor cell survival both in the presence or absence of chemothera...
ORGANISM(S): Mus musculus 
Warburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis
ORGANISM(S): Homo Sapiens 
2023-07-10 | PXD043632 |
PIPKIγ promotes tumor growth by facilitating Warburg effect in colorectal cancer
Tumor cells exhibit aberrant metabolism characterized by high glycolysis even in the presence of oxygen. This metabolic reprogramming, known as the Warburg effect, provides tumor cells with the substrates and redox potential required for the generation of biomass. Here, we show that the mitochondria...
ORGANISM(S): Mus musculus 
MNX1-AS1, a c-Myc induced lncRNA, promotes the Warburg effect by regulating PKM2 nuclear translocation
Epigenetic Targeting of the Warburg Effect by Inhibition of Histone-Deacetylases Leads to Activation of Oxidative Metabolism
A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer. Zheng et al.
Analysis of gene alterations in SW480 cells upon PIPKIγ knockdown. Our findings reveal a new regulatory role of PIPKIγ in Warburg effect and provide a key contributor in colorectal cancer metabolism with potential therapeutic potentials.
ORGANISM(S): Homo sapiens 
2019-05-07 | GSE130761 | GEO
LINC00365 suppresses breast tumor growth and metastasis by inhibiting the HIF-1α-mediated Warburg effect
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