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GenomicsApplication of Microdroplet PCR for Large-Scale Targeted Bisulfite Sequencing
Cytosine methylation of DNA CpG dinucleotides in gene promoters is an epigenetic modification that regulates gene transcription. While many methods exist to interrogate methylation states, no current methods offer large-scale, targeted, single CpG resolution. We report an approach combining bisulf...
ORGANISM(S): Homo sapiens 
2011-06-25 | E-GEOD-30179 | biostudies-arrayexpress
TranscriptomicsQS wild type and Aldh1a1-/- preadipocytes 2015
The goal of this study was to identify preadipocyte signature genes that are dependent in aldehyde dehydrogenase 1a1 (Aldh1a1) by comparison genomes of the immortalized wild type and Aldh1a1-/- preadipocytes. Gene expression was measured using theAffymetrix GeneChip Mouse Gene ST 2.0 arrays. Murine ...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-69573 | biostudies-arrayexpress
TranscriptomicsEffect of fluoxetine treatment on translational profiles of S100a10 cortical pyramidal cells
Molecular phenotyping of cell types and neural circuits underlying pathological neuropsychiatric conditions and their responses to therapy provides one avenue for the development of more specific and effective treatments. In this study, we identify a cell population in the cerebral cortex that shows...
ORGANISM(S): Mus musculus 
2012-05-31 | E-GEOD-35761 | biostudies-arrayexpress
TranscriptomicsEffect of fluoxetine treatment on translational profiles of Glt25d2 cortical pyramidal cells
Molecular phenotyping of cell types and neural circuits underlying pathological neuropsychiatric conditions and their responses to therapy provides one avenue for the development of more specific and effective treatments. In this study, we identify a cell population in the cerebral cortex that shows...
ORGANISM(S): Mus musculus 
2012-05-31 | E-GEOD-35763 | biostudies-arrayexpress
TranscriptomicsEffect of fluoxetine treatment on translational profiles of S100a10 cortical pyramidal cells in p11 KOs
Molecular phenotyping of cell types and neural circuits underlying pathological neuropsychiatric conditions and their responses to therapy provides one avenue for the development of more specific and effective treatments. In this study, we identify a cell population in the cerebral cortex that shows...
ORGANISM(S): Mus musculus 
2012-05-31 | E-GEOD-35765 | biostudies-arrayexpress
UnknownPreliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa.
Not available
S-EPMC8360544 | biostudies-literature
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