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GenomicsThe oncogenic microRNA hsa-mir-155-5p targets the transcription factor ELK3 and links it to the hypoxia response and the Hypoxia Inducible Factor HIF1M-NM-1
The molecular response to hypoxia is a critical cellular process implicated in cancer, and a target for drug development. The activity of the major player, HIF1M-NM-1,M-BM- is regulated at different levels, including the transcriptional level by the Ets factor ELK3. The molecular mechanisms of this ...
ORGANISM(S): Homo sapiens 
2014-12-04 | E-GEOD-60156 | biostudies-arrayexpress
TranscriptomicsCIT_VADS_BW_OMICS
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net); Integrative study based on 89 patients with Head and Neck Squamous Cell Carcinoma (HNSCC); 89 Affymetrix HG-U133 Plus 2.0 GeneChips arrays; 88 samples on HumanCNV370-Quad Ge...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-MTAB-1328 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human hypopharyngeal cancer samples
Gene expression analysis of a unique HNSCC (Head and Neck Squamous Cell Carcinoma) localization, the hypopharynx. Four normal and 34 tumor samples were analysed using Affymetrix HG-U95A microarrays containing probe sets representing ~12650 distinct transcription features.
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2379 | biostudies-arrayexpress
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