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Gene amplification, copy-number increases of particular genes and surrounding genomic segments, promotes cancer progression and acquired therapy resistance. Thus, understanding genetic traits that confer gene amplification proficiency is important. The primary step for gene amplification is sponta...
ORGANISM(S): Cricetulus griseus 
Proteomics on Human breast cancer tissue samples. 9 patients with high risk or 9 patiens low risk MammaPrint breast cancer. Membran fraction. Proteins were reduced, alkylated, digested with Lys-C and Trypsin, and labelled with iTRAQ4plex: 114; high risk; 115; low risk.
ORGANISM(S): Homo sapiens (Human) 
2013-01-08 | PXD000066 | Pride
Pyocyanin has been shown to engage in redox transfer of electrons from NADPH to oxygen to generate superoxide radicals. Transcriptional response to oxygen stress has been characterized in yeast and should be observable upon exposure to pyocyanin if this is the true mode of action. We used microarra...
ORGANISM(S): Saccharomyces cerevisiae 
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