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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
UnknownRandomized phase 2 trial of NP001-a novel immune regulator: Safety and early efficacy in ALS.
Not available
S-EPMC4396529 | biostudies-literature
TranscriptomicsArabidopsis transcriptome responses to mitochondrial perturbations
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29269 | biostudies-arrayexpress
TranscriptomicsInhibition of the mitochondrial TCA cycle by monofluoroacetate in Arabidopsis thaliana
Plant mitochondria signal to the nucleus leading to altered transcription of nuclear genes by a process called mitochondrial retrograde regulation (MRR). MRR is implicated in metabolic homeostasis and responses to stress conditions. Transcriptional consequences on nuclear gene expression of mitochon...
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29268 | biostudies-arrayexpress
TranscriptomicsInhibition of the mitochondrial electron transport chain by antimycin A in Arabidopsis thaliana
Plant mitochondria signal to the nucleus leading to altered transcription of nuclear genes by a process called mitochondrial retrograde regulation (MRR). MRR is implicated in metabolic homeostasis and responses to stress conditions. Transcriptional consequences on nuclear gene expression of mitochon...
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29204 | biostudies-arrayexpress
UnknownEffect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial.
Not available
S-EPMC8787685 | biostudies-literature
GenomicsTranscription Dynamically Patterns the Meiotic Chromosome-Axis Interface
Meiotic chromosomes are highly compacted yet remain transcriptionally active. To understand how chromosome folding accommodates transcription, we investigated the assembly of the axial element, the proteinaceous structure that compacts meiotic chromosomes and promotes recombination and fertility. We...
ORGANISM(S): Saccharomyces cerevisiae SK1 
2015-08-07 | E-GEOD-70112 | biostudies-arrayexpress
UnknownCriteria for Pediatric Sepsis-A Systematic Review and Meta-Analysis by the Pediatric Sepsis Definition Taskforce.
Not available
S-EPMC8670345 | biostudies-literature
GenomicsWhole Genome Sequencing of a Triple Negative Breast Cancer Patient: Matched Primary Tumor, Normal, Metastasis and Xenograft samples

Breast Cancer Subject Participant ID 700064 (Source Sample names: 6888 and 206). We used massively parallel DNA sequencing technologies to screen entire genomes, in an unbiased manner, for genetic changes associated with tumor growth and metastasis. We describe the complete genome sequence ...

phs000245.v1.p1 | EGA
UnknownInternational Consensus Criteria for Pediatric Sepsis and Septic Shock.
Not available
S-EPMC10900966 | biostudies-literature
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