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WDR82 suppresses breast cancer progression by inhibiting ERK-driven chemokine expression and neutrophil infiltration
WDR82 Code Coordinates Transcription and pre-mRNA 3’-End Processing Through Regulated Phosphorylation
Elucidating tumor-intrinsic mechanisms that drive immune evasion and shape an immunosuppressive tumor microenvironment (TME) is essential for overcoming resistance to cancer immunotherapy and developing novel therapeutic strategies. WDR82, a member of the WD-40 protein family, exhibits context-depen...
ORGANISM(S): Mus musculus 
2026-06-25 | GSE325774 | GEO
Phosphorylation plays a central role in coordinating transcription with pre-mRNA maturation, yet the mechanistic understanding of how transcription is regulated by phosphorylation remains limited. The PP1 phosphatase removes CDK9-dependent phosphorylation of Pol II and Spt5, triggering transcription...
ORGANISM(S): Schizosaccharomyces pombe 
2026-07-30 | PXD081886 | Pride
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