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TranscriptomicsReversible Burst of Transcriptional Changes During Induction of Crassulacean Acid Metabolism (CAM) in Talinum triangulare
Rapid, reversible induction of crassulacean acid metabolism in conjunction with pronounced reconfiguration of carbon metabolism enables T. triangulare to survive cycles of severe drought. RNA was extracted from leaves of Talinum triangulare plants (3 biological replicates) after plants were grown un...
ORGANISM(S): Talinum fruticosum 
2015-11-05 | E-GEOD-70601 | biostudies-arrayexpress
GenomicsGenome-wide CRISPR-Cas9 knockout screen in MCF10A with ATP-competitive inhibition of CDC7 (XL-413)
The coordinated activation of DNA replication origins is important for efficient DNA synthesis and genome stability. S-phase cyclin dependent kinases (CDKs) together with CDC7 kinase, are essential to origin activation by converting the pre-replicative complex into a fully active helicase. To identi...
ORGANISM(S): Homo sapiens 
2026-09-30 | E-MTAB-17434 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Candida albicans cells of the wildtype strain SC5314 and a sky2 deletion mutant grown on different carbon sources (glucose, malic acid, succinic acid)
RNA-sequencing was performed to investigate the role of the Candida albicans protein kinase Sky2 in metabolic adaptation to alternative carbon sources. The Candida albicans wildtype strain SC5314 and a sky2 deletion mutant were grown in medium with either glucose (3h), malic acid (6h) or succinic ac...
ORGANISM(S): Candida albicans 
2026-04-01 | E-MTAB-16222 | biostudies-arrayexpress
ProteomicsIdentification of novel biomarker candidates for the immunohistochemical diagnosis of cholangiocellular carcinoma - LC-MS Part
The aim of this study was the identification of biomarkers for the immunohistochemical diagnosis of cholangiocellular carcinoma (CCC). CCC is a primary cancer which arises from the epithelial cells of the bile ducts and is characterised by high mortality rates due to its late clinical presentation a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000082885 | MassIVE
TranscriptomicssnRNA-seq of cortices from a MCT8-OATP1C1-deficient Allan-Herndon-Dudley Syndrome mouse model
Allan-Herndon-Dudley syndrome (AHDS) is a rare disorder caused by faulty thyroid hormone transport to the brain, leading to severe movement problems and intellectual disability. Our study in a murine model of the AHDS used snRNAseq to gain deep insights into individual cortical cells, aiming to unra...
ORGANISM(S): Mus musculus 
2026-08-07 | E-MTAB-16567 | biostudies-arrayexpress
Genomics2013-11-19-17-24-36-breez-MB-2013-10-18-Whole_exome_DNAseq_Medulloblastoma - samples
Illumina HiSeq sequence data (with >80x coverage) were aligned to the hg19 human reference genome assembly using BWA (Li and Durbin, 2009); duplicate reads were removed from the final BAM file. No realignment or recalibration was performed. The whole exome sequencing data of 20 SHH medulloblastomas ...
EGAD00001000698 | EGA
GenomicsRNA-SEQ_DATA_SET_rain_PA_2012_10_22 - samples
Pilocytic Astrocytoma ICGC PedBrain RNA sequencing
EGAD00001000617 | EGA
GenomicsDATA_SET_ICGC_PedBrain_Tumor_Low-Grade_Astrocytoma_Study - samples
Pilot study Pilocytic Astrocytoma ICGC PedBrain, whole genome sequencing of 5 tumors and matched blood
EGAD00001000271 | EGA
GenomicsWGS-SEQ_DATA_SET_rain_PA_2012_10_22 - samples
Pilocytic Astrocytoma ICGC PedBrain whole genome sequencing
EGAD00001000616 | EGA
GenomicsWhole-genome sequencing analysis of low-grade astrocytomas within the ICGC PedBrain Tumor Project
In order to investigate the full range of genetic alterations contributing to the tumourigenesis of low-grade astrocytoma, we have conducted a next-generation sequencing-based analysis on a large series of matched tumor-normal pairs. This study, conducted by the International Cancer Genome Consortiu...
EGAS00001000381 | EGA
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