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We analyzed the genome-wide binding of Tet1 in control (shScr) and Tet1 knockdown (shTet1) mouse ES cells using two different Tet1 antibodies (Tet1-C and Tet1-N). Furthermore, we generated genome-wide mapping of hydroxymethyl cytosine (hmC) and methyl cytosine (mC). We find that hmC, in contrast to ...
ORGANISM(S): Mus musculus 
RNA-seq dataset used to compare the transcriptome of the Atlantic salmon (Salmo salar) tongue and olfactory rosette, in control and infected fish (Yersinia ruckeri). Tongue samples from control also used to describe gene expression in the salmon tongue.
ORGANISM(S): Salmo salar 
Investigate the role of the salmon (Salmo salar) tongue as a potential first-line immune organ by describing the tongues genetic response to an in vivo infection by the bacterial pathogen Yersinia ruckeri.
ORGANISM(S): Salmo salar 
Female cystic fibrosis (CF) patients are confronted with fertility deficiency, experiencing difficulties in getting pregnant. Previous findings using CF mouse models indicate that CF negatively impacts female fertility in mice as it does in humans. Underlying reasons remain elusive. In particular, i...
ORGANISM(S): Mus musculus 
Female cystic fibrosis (CF) patients are confronted with fertility deficiency, experiencing difficulties in getting pregnant. Underlying reasons remain elusive. In particular, it has only poorly been studied whether the endometrium, the inner lining of the womb and crucial tissue for embryo implanta...
ORGANISM(S): Homo sapiens 
Chronic stress is a key risk factor for a variety of diseases, but the determinants of individual stress susceptibility are still unclear. Using a recently developed paradigm for chronic social stress in mice we identified animals that were resistant or susceptible to the persistent effects of chron...
ORGANISM(S): Mus musculus 
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