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UnknownVitis rotundifolia Genes Introgressed with RUN1 and RPV1: Poor Recombination and Impact on V. vinifera Berry Transcriptome.
Not available
S-EPMC11314213 | biostudies-literature
GenomicsHigh-resolution mapping defines the cooperative architecture of Polycomb Response Elements
Polycomb-mediated chromatin repression modulates gene expression during development in metazoans. Binding of multiple sequence-specific factors at discrete Polycomb Response Elements (PREs) is thought to recruit repressive complexes that spread across an extended chromatin domain. To dissect the str...
ORGANISM(S): Drosophila melanogaster 
2014-02-08 | E-GEOD-47829 | biostudies-arrayexpress
UnknownCombined BRAF (Dabrafenib) and MEK inhibition (Trametinib) in patients with BRAFV600-mutant melanoma experiencing progression with single-agent BRAF inhibitor.
Not available
S-EPMC4226803 | biostudies-literature
TranscriptomicsEffect of methylphenidate on gene expression profiles of Attention Deficit Hyperactivity Disorder patients and unaffected controls.
Attention deficit hyperactivity disorder (ADHD) is a common psychiatric condition of children with a prevalence of 5-10% worldwide. Up to 30% of adults with a history of childhood ADHD maintain symptoms in later life; these adult ADHD patients are severely impaired in social and professional life d...
ORGANISM(S): Homo sapiens 
2014-09-05 | E-GEOD-52889 | biostudies-arrayexpress
TranscriptomicsMLL2 facilitates long-range gene regulation through LINE1 elements [scRNA-seq]
Transcriptional regulation is tightly linked to chromatin organization, with H3K4me3 commonly marking both active and bivalent promoters. In embryonic stem cells (ESC), MLL2 is essential for H3K4me3 deposition at bivalent promoters, which has been proposed to facilitate the induction of major develo...
ORGANISM(S): Mus musculus 
2026-07-12 | E-MTAB-17228 | biostudies-arrayexpress
TranscriptomicsCpG Island methylation variation in placentae of Intra-Uterine Growth Restricted (IUGR) fetuses versus controls
Methylation profiling of CpG Island Methylation of genomic DNA samples extracted from placentae of Intra-Uterine Growth Restricted newborns and gestational age matched controls. These data can be used for methylation comparisons between these two types of samples. The results of such comparisons can...
ORGANISM(S): Homo sapiens 
2011-04-11 | E-GEOD-22326 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of mRNA derived from fourth larval stage larvae from C. elegans strain PE1328 treated for 16 hours at 20 degrees Celsius with 5-Ph-IAA compared to untreated controls
The objective of the experiment was to determine the impact of cap-adjacent 2'-O-ribose methylation on steady-state mRNA levels in a background lacking the decapping exonculease EOL-1. We depleted CMTR-1 protein, which is the main enzyme responsible for of cap-adjacent 2'-O-ribose methylation in C. ...
ORGANISM(S): Caenorhabditis elegans 
2026-03-05 | E-MTAB-16687 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of grafting and wounding grapevine stems
Grafting plants uses intrinsic healing processes to join two different plants together to create one functional organism. To further our understanding of the molecular changes occurring during graft union formation in grapevine, we characterized the transcriptome of intact and wounded cuttings (with...
ORGANISM(S): Vitis vinifera 
2025-05-01 | E-MTAB-14101 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis Rhinolophus ferrumequinum (Rfe) cells upon poly-I:C transfection
Transcriptome analysis Rhinolophus ferrumequinum (Rfe) cells upon poly-I:C transfection. Rfe cell expressing human ACE2 and TMPRSS2 (Rfe-AT) and a SARS-Cov-2 / BANAL-236 successible clonal Rfe-AT cell line (Rfe-ATC) were transfected with poly-I:C or PBS and transcriptome was analysed using RNA seque...
ORGANISM(S): Rhinolophus ferrumequinum 
2026-04-10 | E-MTAB-16878 | biostudies-arrayexpress
TranscriptomicsMammalian PERIOD complex regulates repair of DSB in active chromatin through anchoring to the nuclear envelope
Repair of DNA Double Strand Breaks produced in transcriptionally active chromatin occurs through a mechanism, Transcription-Coupled DSB repair (TC-DSBR), that is yet poorly characterized. Here, using a screening approach scoring multiple outputs in human cells, we identified the PER complex, a key m...
ORGANISM(S): Homo sapiens 
2025-11-12 | E-MTAB-12712 | biostudies-arrayexpress
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