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TranscriptomicsAPOL1 renal-risk variants induce mitochondrial dysfunction (Illumina)
To elucidate pathways whereby apolipoprotein L1 gene (APOL1) G1 and G2 variants facilitate kidney disease in African Americans, human embryonic kidney cells (HEK293) were used to establish doxycycline-inducible (Tet-on) cell lines stably expressing reference APOL1 G0 and its G1 and G2 renal-risk var...
ORGANISM(S): Homo sapiens 
2016-08-23 | E-GEOD-85918 | biostudies-arrayexpress
TranscriptomicsAPOL1 renal-risk variants induce mitochondrial dysfunction (Affymetrix 2)
To assess differential gene expression by APOL1 renal-risk (2 risk alleles) vs. non-risk (G0G0) genotypes in primary proximal tubule cells (PTCs), global gene expression (mRNA) levels were examined on Affymetrix HTA 2.0 arrays in primary PTCs cultured from non-diseased kidney in African Americans wi...
ORGANISM(S): Homo sapiens 
2016-08-23 | E-GEOD-85920 | biostudies-arrayexpress
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