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TranscriptomicsChromatin immunoprecipitation in yeast for different affinity-tagged strains (two genotypes compared with wild type)
RNA immunoprecipitation from different affinity-tagged strains. Each hyb compared to a common total RNA.
ORGANISM(S): Schizosaccharomyces pombe 
2004-11-09 | E-MEXP-208 | biostudies-arrayexpress
TranscriptomicsComparison between HuT78 parental and romidpepsin-selected cell lines
Gene expression values were determined for HuT78 parental cells and cells selected with romidpesin in the presence of P-glycoprotein inhibitors. HuT78 DpVp35 cells are maintained in 35 ng/ml romidepsin with 2.5 µg/ml verapamil and HuT78 DpP100 cells are maintained in 100 ng/ml romidepsin with 1 µM v...
ORGANISM(S): Homo sapiens 
2013-03-12 | E-GEOD-45018 | biostudies-arrayexpress
MetabolomicsPRDM15 is a master regulator of metabolism essential to sustain B-cell lymphomagenesis
PRDM family members are sequence-specific transcriptional regulators involved in cell identity and fate determination and are often dysregulated in cancer. The PRDM15 gene is of particular interest, given its relatively low expression in adult tissues and its overexpression in follicular lymphomas (...
2025-06-16 | MTBLS1639 | MetaboLights
TranscriptomicsGene expression profiles of Herceptin-resistant breast cancer cells
Herceptin (trastuzumab) is a humanized monoclonal antibody targeted to the Her2 receptor tyrosine kinase. Despite a robust response rate to Herceptin-based therapies in Her2-positive patients, resistance frequently arises within one year of the initial response. To address the mechanism of Hercept...
ORGANISM(S): Homo sapiens 
2009-08-21 | E-GEOD-15043 | biostudies-arrayexpress
TranscriptomicsClusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis
Clusterin (CLU) is a stress-activated molecular chaperone that confers treatment resistance to taxanes when highly expressed. While CLU inhibition potentiates activity of taxanes and other anti-cancer therapies in preclinical models, progression to treatment resistant disease still occurs implicatin...
ORGANISM(S): Homo sapiens 
2016-03-01 | E-GEOD-67256 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of broiler liver transcriptome reveals novel responses to heat stress
Background In broilers, heat stress can result in reduced feed consumption, digestive inefficiency, impaired metabolism, and even death. The broiler sector of the U.S. poultry industry incurs approximately $52 million in heat stress-related losses annually. The objective of this study is to charac...
ORGANISM(S): Gallus gallus 
2013-09-20 | E-GEOD-51035 | biostudies-arrayexpress
TranscriptomicsGene expression of RonTK-/- mammary glands compared to RonTK+/+ controls during development
RON WT and RON KO at 5, 6, 7 week virgin mammary glands In the study, we demonstrated that RON regulates mammary gland branching morphogenesis in pubertal development associated with changes in gene expression. Keywords: Pubertal mammary glands In the study, we hybridized RNA from 5, 6, 7 week old ...
ORGANISM(S): Mus musculus 
2009-06-16 | E-GEOD-16629 | biostudies-arrayexpress
TranscriptomicsTranscriptomic Signature of Trophoblast Differentiation in a Human Embryonic Stem Cell Model
Identification of genes involved in trophoblast differentiation is of great interest in understanding cellular and molecular mechanisms involved in placental development and is relevant clinically to fetal development, fertility, and maternal health. To understand, on a global scale, changes in the ...
ORGANISM(S): Homo sapiens 
2011-09-16 | E-GEOD-30915 | biostudies-arrayexpress
UnknownCasirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC8830904 | biostudies-literature
UnknownAspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC8598213 | biostudies-literature
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