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GenomicsGlobal Mapping of Histone H3 K4 and K27 Trimethylation: Lineage Fate Determination of Differentiating CD4+ T Cells
Multipotential naïve CD4+ T cells differentiate into distinct lineages including Th1, Th2, Th17, and inducible T regulatory (iTreg) cells. The remarkable diversity of CD4+ T cells begs the question whether the observed changes reflect terminal differentiation with heritable epigenetic modifications ...
ORGANISM(S): Mus musculus 
2009-01-21 | E-GEOD-14254 | biostudies-arrayexpress
UnknownOCIAD1 contributes to neurodegeneration in Alzheimer's disease by inducing mitochondria dysfunction, neuronal vulnerability and synaptic damages.
Not available
S-EPMC6957876 | biostudies-literature
TranscriptomicsS. coelicolor YSK3225 R5- Medium Time-course Study (Culture #2)
Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this stud...
ORGANISM(S): Streptomyces coelicolor 
2010-06-10 | E-GEOD-8109 | biostudies-arrayexpress
TranscriptomicsS. coelicolor YSK4425 R5- Medium Time-course Study (Culture #1)
Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this stud...
ORGANISM(S): Streptomyces coelicolor 
2010-06-10 | E-GEOD-8110 | biostudies-arrayexpress
TranscriptomicsS. coelicolor M145 SMM medium time course study (Culture # 2)
Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this study,...
ORGANISM(S): Streptomyces coelicolor 
2012-12-19 | E-GEOD-22395 | biostudies-arrayexpress
TranscriptomicsS. coelicolor M145 SMM medium time course study (Culture # 3)
Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this study,...
ORGANISM(S): Streptomyces coelicolor 
2012-12-19 | E-GEOD-22397 | biostudies-arrayexpress
TranscriptomicsS. coelicolor M145 SMM medium time course study (Culture # 1)
Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this study,...
ORGANISM(S): Streptomyces coelicolor 
2012-12-19 | E-GEOD-22394 | biostudies-arrayexpress
TranscriptomicsS. coelicolor WL6268 R5- medium time course study
Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this study,...
ORGANISM(S): Streptomyces coelicolor 
2010-10-25 | E-GEOD-21808 | biostudies-arrayexpress
TranscriptomicsS. coelicolor YSK3654 R5- medium time course study
Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this study,...
ORGANISM(S): Streptomyces coelicolor 
2010-10-25 | E-GEOD-21807 | biostudies-arrayexpress
TranscriptomicsS. coelicolor LY2517 R5- medium time course study (Culture # 1)
Antibiotic biosynthesis in Streptomyces species is controlled by a complex genetic and biochemical network of global and pathway specific regulators. Details of their precise interactions in mediating temporal and spatial expression of secondary metabolite genes remain poorly defined. In this study,...
ORGANISM(S): Streptomyces coelicolor 
2012-12-19 | E-GEOD-21809 | biostudies-arrayexpress
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