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ProteomicsComparative evaluation of methods for isolating extracellular vesicles from ICC cell culture supernatants: Insights into proteomic and glycomic analysis
Extracellular vesicles (EVs) are specialized nanoscale vesicular structures that act as mediators of intercellular communication, playing crucial roles in the pathological processes of cancers. Aberrant glycosylation is a hallmark of cancer, the analysis of EVs and protein glycosylation provides val...
ORGANISM(S): Homo Sapiens 
2025-03-24 | PXD062160 |
ProteomicsTargeting mitochondria-inflammation circuit by β-hydroxybutyrate mitigates heart failure with preserved ejection fraction
Rationale: Over 50% of heart failure patients have preserved, rather than reduced ejection fraction (HFpEF vs. HFrEF). Complexity of its pathophysiology and the lack of animal models hamper the development of effective therapy for HFpEF. Objective: This study was designed to investigate the metabol...
ORGANISM(S): Mus Musculus 
2021-10-22 | PXD021957 |
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