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With L-glutamine supplemented with 10% fetal bovine serum (FBS) (Gibco) and 1% penicillin-streptomycin (10,000 units/mL penicillin and 10 mg/mL streptomycin) (Gibco). (1)
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UNIPROT ID/AC

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CHEBI ID

CHEBI:15428 (2)
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CHEBI:65172 (1)
CHEBI:68579 (1)
CHEBI:135063 (1)
CHEBI:145243 (1)
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CHEBI:16651 (1)
CHEBI:16668 (1)

Metabolite Name

1a-hydroxy-21-nor-20-oxavitamin D3 (1)
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First Public Date

2014 (9)
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2018 (5)
2019 (4)
2022 (3)
2025 (2)
2021 (2)
2020 (2)
2016 (2)
2015 (2)
2013 (2)
2017 (1)

Modelling Approach

Ordinary differential equation model (3)
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Lab affiliation

University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (18)
Institute for Genetics and CECAD Research Center, University of Cologne, Cologne, Germany (4)
Friedrich Miescher Institute for Biomedical Research, FMI, Switzerland (3)
Institute for Biochemistry, University of Cologne (3)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (2)
Associate Professor, University of Washington (2)
Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Department of Medicine, Brigham Women's Hospital, Harvard Medical School, Boston, MA, United States (2)
Center for Proteomics & Metabolomics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA (2)
Chair of Proteomics and Bioanalytics, Technical University of Munich, Freising, Germany (2)
Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland (2)
Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany (2)
EDyP (2)
Hannover Medical School Institute for Clinical Biochemistry (OE 4340) Carl-Neuberg-Strasse 1 Building J03, Level 04, Room 1291 (Office), Room 1250 (Lab) 30625 Hannover (2)
Keck MS & Proteomics Resource Yale School of Medicine (2)
The Hospital for Sick Children (2)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry ( lab head ) (2)
1 Department of Anaesthesiology, LMU University Hospital, Ludwig-Maximilian-University (LMU), Munich, Germany 2 Walter Brendel Center of Experimental Medicine, Research Unit Immune Function and Immune Metabolism, Ludwig-Maximilian-University (LMU), Munich, Germany (1)
Albert Einstein College of Medicine (1)
Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany (1)
Bavarian Center for Biomolecular Mass Spectrometry at Klinikum rechts der Isar Technical University of Munich (1)
Bioinformatics, TruDiagnostic, USA (1)
Biomolecular mass spectrometry and proteomics group, Utrecht University (1)
Brain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA (1)
Cancer Science Institute of Singapore, National University of Singapore (1)
Center for Cancer Research, Massachusetts General Hospital, Boston MA, USA;Department of Chemistry and Chemical Biology, Harvard University, Cambridge MA, USA. (1)
Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Department of Medicine, Brigham Women's Hospital, Harvard Medical School, Boston, MA, 02115, United States (1)
Centre Médical Universitaire, University of Geneva (1)
Charité – Universitätsmedizin Berlin, Department of Biochemistry, 10117 Berlin, Germany; The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW11AT, UK (1)
Debora Bonenfant, Novartis Institutes for Biomedical Research, Basel, Switzerland (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)

IsPrivate

False (8)

Submitter Keywords

Machine Learning Model (2)
FAIR-AIML (1)

Classification

bacteria (2)

Modification

2x(15)N labeled L-lysine (2)
4x(15)N labeled L-arginine (2)
Not available (1)

Study type

Transcription profiling by array (135)
RNA-seq of coding RNA (31)
ChIP-seq (20)
Comparative genomic hybridization by array (9)
Other (7)
Methylation profiling by high throughput sequencing (5)
Hi-C (4)
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Unknown experiment type (3)
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Genotyping by array (2)
Animal - High-throughput sequencing (1)
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4C (1)
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RNA-seq of non coding RNA (1)

Release Date

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SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia

Acute myeloid leukemia (AML) cells rely on phospho-signaling pathways to gain unlimited proliferation potential. Here, we used domain-focused CRISPR screening to identify the nuclear phosphatase SCP4 as a dependency in AML, yet this enzyme is dispensable in normal hematopoietic progenitor cells. Usi...

2025-05-29 | MTBLS3707 | MetaboLights

Demographically Diverse Substance Use Disorder Cohorts of Dr. Stanley H. Weiss

PRJNA671286 | ENA

Demographically Diverse Substance Use Disorder Cohorts of Dr. Stanley H. Weiss

PRJNA671287 | ENA

Diagnosis of a patient with Sifrim-Hitz-Weiss syndrome, development and epileptic encephalopathy-14, and medium chain Acyl-CoA dehydrogenase deficiency: a case report

PRJEB60020 | ENA

Diagnosis of a patient with Sifrim-Hitz-Weiss syndrome, development and epileptic encephalopathy-14, and medium chain Acyl-CoA dehydrogenase deficiency: a case report

PRJEB60021 | ENA

A Novel Frameshift CHD4 Variant Leading to Sifrim-Hitz-Weiss Syndrome in a Proband with a Subclinical Familial t(17;19) and a Large dup(2)(q14.3q21.1).

Not available

S-EPMC9855399 | biostudies-literature