Sort   by:  
 Page size 
ProteomicsLow-Density Lipoprotein Receptor fuels the cellular cholesterol-mTORC1 axis required for CD8+ T cell activation
In this study, the contribution of cholesterol uptake by the low-density-lipoprotein receptor (LDLR) in the metabolic reprogramming of activated T cells was investigated at proteome level by mass-spectrometry-assisted shotgun proteomics.
ORGANISM(S): Mus musculus (Mouse) 
2022-09-20 | PXD030365 | Pride
Mtorc1 Cholesterol Lfq Cd8+ Ldlr 
ProteomicsMycobacterium tuberculosis under starvation
Mycobacterium tuberculosis was grown in Middlebrook 7H9 medium supplemented with 0.4% glycerol, 0.085% NaCL, 0.5% BSA and 0.05% Tyloxapol in roller bottle culture (2 rpm at 37°C). To induce starvation, exponentially growing bacteria were washed and resuspended in PBS supplemented with 0.025% Tyloxap...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2013-11-22 | PXD000483 | Pride
Mycobacterium tuberculosis Starvation Dda 
UnknownNR0B2 re-educates myeloid immune cells to reduce regulatory T cell expansion and progression of breast and other solid tumors.
Not available
S-EPMC11892351 | biostudies-literature
ProteomicsSecretome of human PBMC after ConA stimulation and incubation with A1 and A2 milk fractions of different molecular weight
There is an ongoing discussion about cow’s milk and its variants primarily focusing on the A1 variant in contrast to the A2 variant and their health-related impacts. The difference between these variants lies in a single amino acid alteration at position 67 of β-casein. This alteration is presumed t...
ORGANISM(S): Homo sapiens (Human) 
2026-07-13 | PXD066232 | Pride
A1/a2 milk Uantitative label-free lc-ms/ms Modulation of immune system Human pbmc 
UnknownGlofitamab, a Novel, Bivalent CD20-Targeting T-Cell-Engaging Bispecific Antibody, Induces Durable Complete Remissions in Relapsed or Refractory B-Cell Lymphoma: A Phase I Trial.
Not available
S-EPMC8210975 | biostudies-literature
TranscriptomicsExpression data of chronic lymphocytic leukemia patient samples from the REACH study
We assessed genome-wide expression of available pretreatment specimens from CLL patients enrolled in REACH, a study of fludarabine and cyclophosphamide FC or R-FC (addition of rituximab to FC) in relapsed CLL, to understand the disease heterogeneity and explore genes that may be prognostic or predic...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-58211 | biostudies-arrayexpress
UnknownThe potential impact of new Andean dams on Amazon fluvial ecosystems.
Not available
S-EPMC5568116 | biostudies-literature
UnknownA human immunodeficiency syndrome caused by mutations in CARMIL2.
Not available
S-EPMC5473639 | biostudies-literature
UnknownAntibody and T-Cell Response to Bivalent Booster SARS-CoV-2 Vaccines in People With Compromised Immune Function: COVERALL-3 Study.
Not available
S-EPMC11481330 | biostudies-literature
MetabolomicsUntargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models
The application of ketogenic diet (KD) (high fat/low carbohydrate/adequate protein) as an auxiliary cancer therapy is a field of growing attention. KD provides sufficient energy supply for healthy cells, while possibly impairing energy production in highly glycolytic tumor cells. Moreover, KD regula...
2019-10-08 | MTBLS1066 | MetaboLights
Sort   by:  
 Page size