Sort   by:  
 Page size 
ProteomicsMyelin-axon interface disruption uncovered by subcellular proteomics and imaging of Alzheimer’s human brain
Myelin ensheathment enables efficient axonal electrical conduction, metabolic support, and regulates neuronal plasticity. Myelin and axon disruptions are involved in Alzheimer’s disease (AD), however, the precise mechanisms of how myelin and axons are decoupled remain poorly understood. Using novel ...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-06-27 | PXD045861 | Pride
Lc-ms-ms Subcellular proteomics Alzheimer's disease Proximity labeling Human brain Myelin-axon interface 
TranscriptomicsOsteoarthritis-related changes in gene expression in knee articular chondrocytes in a rat model of osteoarthritis.
Cartilage destruction in osteoarthritis (OA) results from disturbed chondrocyte metabolism. Here, we used microarrays to show that TGF alpha and CCL2 are simultaneously upregulated in a rat model of OA and cooperate to drive cartilage degradation. The goals of the experiments included here were to a...
ORGANISM(S): Rattus norvegicus 
2012-11-15 | E-GEOD-42295 | biostudies-arrayexpress
UnknownEffects of Ibudilast on MRI Measures in the Phase 2 SPRINT-MS Study.
Not available
S-EPMC7905793 | biostudies-literature
Sort   by:  
 Page size